DYSLIPIDEMIA AMONG SMOKERS
Abstract
ABSTRACT
Objective: The objective of this study is to evaluate lipid profile among cigarette smokers and compare it with non-smokers.
Methods: About 125 subjects aged between 20 and 40 years including 100 smokers as case group and 25 non-smokers as control were taken into
study. They did not having any history of any disease (i.e., diabetes, hypertension, liver diseases, renal diseases, or obesity) or alcohol intake. They
were not taking any drug such as B-blockers, lipid lowering drugs, or thiazide diuretics.
Results: The mean serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), very LDL-C (VLDL-C) were significantly raised (p<0.05) in
all three groups of mild, moderate, and heavy smokers as compared to non-smokers control while mean serum high--density lipoproteins cholesterol
(HDL-C) was significantly lower in all three above said groups.
Conclusion: Cigarette/beedi smoking is associated with lower level of god cholesterol, i.e., HDL, and higher level of cholesterol, triglycerides, and
serum LDL and VLDL.
Keywords: Dyslipidemia, smokers
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REFERENCES
Altuntas I, Dane S, Gümüstekin K. Effects of cigarette smoking on lipid
peroxidation. J Basic Clin Physiol Pharmacol 2002;13(1):69-72.
Rao CS, Subash YE. The effect of chronic tobacco smoking and
chewing on the lipid profile. J Clin Diagn Res 2013;7(1):31-4.
Lakshmi SA, Lakshmanan A, Kumar PG, Saravanan A. Effect of
intensity of cigarette smoking on haematological and lipid parameters.
J Clin Diagn Res 2014;8(7):BC11-3.
Austin MA. Plasma triglyceride and coronary heart disease. Arterioscler
Thromb 1991;11:2-14.
Krishnaswami S, Richard J, Prasad NK, Alexander T, Thomas CS.
Association between cigarette smoking and coronary arterial disease
in patients in India: How quantitative is it? An assessment by selective
coronary arteriography. Int J Cardiol 1991;31(3):305-11.
Stamford BA, Matter S, Fell RD, Sady S, Papanek P, Cresanta M.
Cigarette smoking, exercise and high density lipoprotein cholesterol.
Atherosclerosis 1984;52(1):73-83.
Chelland Campbell S, Moffatt RJ, Stamford BA. Smoking and smoking
cessation -- The relationship between cardiovascular disease and
lipoprotein metabolism: A review. Atherosclerosis 2008;201(2):225-35.
Dhalla NS, Temsah RM, Netticadan T. Role of oxidative stress in
cardiovascular diseases. J Hypertens 2000;18(6):655-73.
Available from: http://www.spinreact.com/files/Inserts/Bioquimica/
BSIS11_COLEST._02-2014.pdf.
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the
concentration of low-density lipoprotein cholesterol in plasma, without
use of the preparative ultracentrifuge. Clin Chem 1972;18(6):499-502.
McGowan MW, Artiss JD, Strandbergh DR, Zak B. A peroxidasecoupled
method for the colorimetric
determination of
serum
triglycerides.
Clin Chem 1983;29(3):538-42.
Trinder P. Determination of blood glucose using an oxidase– peroxidase
system with a non-carcinogenic chromogen. Ann Clin Biochem
;6:24-30.
Adedeji OA, Etukudo MH. Lipid profile of cigarette smokers in Calabar
municipality. Pak J Nutr 2006;5(30):237-38.
Ayaori M, Hisa T, Suzukawa M, Yoshida H, Nishiwaki M, Ito T,
et al Plasma level and redox status of ascorbic acid and level of lipid
peroxidation product in active and passive smokers. Environ Health
Perspect 2000;108(2):105-8.
Neki NS. Lipid profile in chronic smokers - A clinical study. Indian
Acad Clin Med 2005;3(1):51-4.
Jaleel A, Jaleel F, Majeed R, Alam E. Leptin and blood lipid level in
smokers and ex smokers. World Appl Sci J 2007;2(4):248-352.
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