A BRIEF REVIEW ON RECENT DEVELOPMENTS AND EXPLORING ACTIVITIES OF 4-THIAZOLIDINONE

Authors

  • Arunlal V. B Devaki amma Memorial College of pharmacy, Chelembra, Malappuram DT, Kerala, 673634, India
  • Vandana K.
  • Biju C. R.

Abstract

The present article is sincere attempt to review chemistry, synthesis, and applications of 4-thiazolidinone. Thiazolidinone, a saturated form of thiazole with carbonyl group on fourth carbon, has been considered as a magic moiety (wonder nucleus) which posses almost all types of biological activities. It belongs to an important group of heterocyclic compounds containing sulfur and nitrogen in a five-member ring. This biologically active scaffold has encouraged our interest in synthesizing several new compounds by using several substitutions at different positions, attached to 4-thiazolidinone moieties [1]. Thiazolidinone scaffolds are reviewed extensively in literature for its vibrant potential against several activities. The various substituted 4-thiazolidinone has shown a wide spectrum of biological activities. The literature reveals that 4-thiazolidinone has diverse biological potential, and the easy synthetic routes for synthesis have taken attention of the chemists, pharmacologists and researchers. By the present scenario it can be concluded that 4-thiazolidinones have a great potential which remain to be disclosed till date.

Keywords: Thiazolidinone, Thiazole, Pharmacological activities.

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Published

10-04-2015

How to Cite

B, A. V., V. K., and B. C. R. “A BRIEF REVIEW ON RECENT DEVELOPMENTS AND EXPLORING ACTIVITIES OF 4-THIAZOLIDINONE”. International Journal of Current Pharmaceutical Research, vol. 7, no. 2, Apr. 2015, https://mail.innovareacademics.in/journals/index.php/ijcpr/article/view/6272.

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Section

Review Article(s)