A PREVENTIVE APPLICATION IMPROVIZED USING ARID PLANT DERIVATES: NOSOCOMIAL PREVENTIVE REMEDY

Authors

  • Itishree Kaushik
  • Manali Datta Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur

Abstract

ABSTRACT
Objective: Epidermis acts as a niche for plethora of infection causing bacteria. It is a necessity to maintain the microbial populations in acceptable
levels to attain hygienic conditions. In this study, an attempt has been made to prepare and test the functioning of antimicrobial cloth using desert
plant extracts.
Methods: Comparative antibacterial and radical scavenging activity of the aqueous and methanolic extracts from plants namely Saccharum
spontaneum, Prosopsis cineria and Balanites aegyptica was tested. Minimum inhibitory concentration (MIC) against Staphylococcus aureus MTCC 7443,
Streptococcus pneumonia MTCC 655, Escherichia coli NCIM 2642, Pseudomonas aeroginosa MTCC 8295, Bacillus megaterium NCIM 2326, Bacillus
subtilis NCIM 2329 ranged from 20 µg to 50 µg for the various extracts utilized. DNAse activity was also checked for the extracts to estimate the
potency of extract for skin damage.
Results: Based on the MIC ranges, an excess amount (100 µg) of the extract was loaded on the cotton cloth and check for antimicrobial potential. DNAse
activity was also checked for the extracts to estimate the potency of extract for skin damage. No extract tested was found to have DNA degradation
activity.
Conclusion: Based on the manifested results, cotton cloth loaded with 100 µg/cm
of crude extracts from Balanites aegyptica may be successfully
used as an antimicrobial cloth. Fabrics capable of sterilization would have potential benefits to reduce disease transfers among hospital populations
and bio‑warfare protection.
Keywords: Balanites aegyptica, Antimicrobial, Cotton cloth, Desert plant extract, Skin microflora.
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Author Biography

Manali Datta, Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur

Amity Institute of Biotechnology

Assistant Proffessor and Program co-ordinator

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Published

01-03-2016

How to Cite

Kaushik, I., and M. Datta. “A PREVENTIVE APPLICATION IMPROVIZED USING ARID PLANT DERIVATES: NOSOCOMIAL PREVENTIVE REMEDY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 2, Mar. 2016, pp. 150-3, https://mail.innovareacademics.in/journals/index.php/ajpcr/article/view/10178.

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