STUDY OF IN VITRO ANTI-INFLAMMATORY ACTIVITY OF ETHNOMEDICINAL PLANTS OF SIKKIM VISCUM ARTICULATUM AND ACORUS CALAMUS
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Objective: The present study was carried out to evaluate the anti-inflammatory property of ethnomedicinal plants Viscum articulatum and Acorus
calamus.
Methods: Human red blood cells membrane stabilization method was applied to assess the anti-inflammatory property of both the plants.
Results: It was observed that both plant extracts have the anti-inflammatory potential comparable with that of the drug indomethacin. However, A.
calamus was found to provide slightly more inhibition of hemolysis (76.8%) than that of standard drug (indomethacin) (72.8%), whereas V. articulatum
provided slightly lesser inhibition (68%) in comparison to the drug. There was the tendency of increase protection along with the increase in the
concentration of the extract, and maximum protection was achieved at the maximum concentration of 5000 µg/ml.
Conclusion: The study proves the anti-inflammatory efficacy of both the plants and they hold a good prospect for drug development against
inflammation.
Keywords: Anti-inflammatory, Viscum articulatum, Acorus calamus, Sikkim.
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