EVALUATION OF PHENOL CONTENT, ANTIOXIDANT, AND PROTEINASE INHIBITORY ACTIVITY OF PLANT DERIVED PROTEASE INHIBITORS OF EIGHT ANTI-DIABETIC PLANTS

Authors

  • Vinyas Mayasa KLE University
  • Vijay Kumar Rasal
  • Banappa S Unger

Abstract

Objective: The objective of this study was to partially purified from the eight known anti-diabetic plants and evaluated for the total phenol, protease
inhibitory (PI) activity, and antioxidant activity.
Methods: PI activity was performed using casein as substrate. The total phenolic content was estimated by folin-ciocatechu reagent method. The
antioxidant activity was estimated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) model and hydrogen peroxide scavenging activity.
Results: The results shown that Syzygium cumini has the highest total phenol and protein content. Solanum tuberosum has the highest percentage
PI activity. In DPPH model of antioxidant in SC has the highest inhibitory activity, whereas in the hydrogen peroxide scavenging activity Momardica
charantia has the maximum inhibition.
Conclusion: These data once again prove that phenolic compounds have statistically significant antioxidant activity. Among all the PIs ST has
maximum inhibition activity. To conclude, all these PIs can be an excellent source of antioxidants.
Keywords: Antioxidant, Plant protease inhibitor, Phenolic, Hydrogen peroxide, Protein content.

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Author Biography

Vinyas Mayasa, KLE University

PhD Research Scholar,

KLE University ,

Belagavi

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Published

01-05-2016

How to Cite

Mayasa, V., V. Kumar Rasal, and B. S. Unger. “EVALUATION OF PHENOL CONTENT, ANTIOXIDANT, AND PROTEINASE INHIBITORY ACTIVITY OF PLANT DERIVED PROTEASE INHIBITORS OF EIGHT ANTI-DIABETIC PLANTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 9, no. 3, May 2016, pp. 215-9, https://mail.innovareacademics.in/journals/index.php/ajpcr/article/view/11117.

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