PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL SCREENING OF AAVAARAI VIDHAI CHOORANAM

Authors

  • Uma Ks Department of Siddha, The Tamil Nadu Dr. M. G. R. Medical University, Chennai - 600 032, Tamil Nadu, India
  • Parthiban P Department of Indian Medicine and Homoeopathy, Arumbakkam, Chennai - 600 106, Tamil Nadu, India
  • Kalpana S Department of Epidemiology, The Tamil Nadu Dr. M. G. R. Medical University, Chennai - 600 032, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i10.19422

Keywords:

Cassia auriculata, Siddha formulations, Organoleptic characters, Physiochemical properties, Preliminary phytochemical analysis, Aavaarai vidhai chooranam

Abstract

 

 Objective: To study the organoleptic characters, physio chemical properties and preliminary phytochemicals screening of Siddha formulations Aavaarai Vidhai Chooranam (AVC).

Methods: The study drug, AVC was prepared as per procedure given in the text Neerizhivu maruthuvam. Organoleptic characteristics were assessed by appearance, colour, taste and odour. The physiochemical property of trial drug was screened for moisture content, total ash value, acid insoluble ash, water soluble extractive value, alcohol soluble extractive value, pH, reducing sugar, total sugar, total solid content and fat content. Preliminary Phytochemical evaluation of AVC was carried out by the standard procedure. The drug was screened for alkaloids, amino acids & proteins, anthraxquinone, carbohydrate, flavonoids, glycosides, phenols quinones, resins, saponins, steroids tanins, terpenoids and sugar. For which the aqueous extraction of the trial drug was taken by dissolving the 5 g of sample with 50 ml of distilled water and heated over water bath at 60°C. Then extract was filtered and used the filtrates for testing.

Results: The trial drug, AVC shown organoleptic characters as per literature evidence, physiochemical properties as moisture content, total ash value, acid insoluble ash, water soluble extractive value, alcohol soluble extractive value, pH, reducing sugar, total sugar, total solid content and fat content were found within normal limits, preliminary phytochemical test showed the presence of flavonoids, tannins, steroids, terpenoids, alkaloids, carbohydrate, proteins, phenols and sugar.

Conclusion: Organoleptic characters, physio chemical properties and preliminary photochemica shows that the drug has the quality and potency to treat against diabetes mellitus. To confirm this activity, further research should be done to assess the safety and efficacy of the drug AVC.

Downloads

Download data is not yet available.

Author Biographies

Uma Ks, Department of Siddha, The Tamil Nadu Dr. M. G. R. Medical University, Chennai - 600 032, Tamil Nadu, India

Associate professor,

Department of siddha

Parthiban P, Department of Indian Medicine and Homoeopathy, Arumbakkam, Chennai - 600 106, Tamil Nadu, India

Joint Director

Department of Indian Medicine and Homoeopathy

chennai-106

Kalpana S, Department of Epidemiology, The Tamil Nadu Dr. M. G. R. Medical University, Chennai - 600 032, Tamil Nadu, India.

Associate professor,

Department  of Noi Naadal

 

 

References

Tiwari P, Kumar B, Kaur M, Kaur G, Kaur H. Phytochemical screening and extraction-review. Int Pharm Sci 2011;1(1):98-106.

Deshpande AD, Harris-Hayes M, Schootman M. Epidemiology of diabetes and diabetes-related complications: Diabetes special issue. Phys Ther 2008;88(11):1254-63.

Raj JY, Peter MP, Joy V. Chemical compounds investigation of Cassia auriculata seeds: A potential folklore medicinal plant. Asian J Plant Sci Res 2012;2(2):187-92.

Soundharajan SR, Ponnusamy RD. Chemical composition and characterization studies of Cassia auriculata flower extract. Int J Pharm Pharm Sci 2014;6(7):327-30.

Ashok JP, Harish PH, Prasad WV, Ashok WP. Comparative assessment of antioxidant potential of Cassia auriculata (Linn.) flower, leaf and seed methanolic extracts. Int J Pharm Pharm Sci 2015;7(9):381-5.

Joy V, Peter MP, Raj JY, Ramesh. Medicinal values of avaram (Cassia auriculata Linn.): A review. Int J Curr Pharm Res 2012;4(2):1-3.

Daisy P, Kani FG. Hypolipidemic and hepatoprotective effects of Cassia auriculata Linn bark extracts on streptozotocin induced diabetics in male Wister albino rats. Asian J Pharm Clin Res 2013;6(2):43-8.

Mudaliar KS. Gunapadam Porutpanbu Nool. Part-1, Mooligai Vagupu. 7th ed. Chennai: Department of Indian Medicine and Homeopathy, Government of Tamil Nadu; 2003.

Luthra PM, Singh R, Chandra R. Therapeutic uses of Curcuma longa (turmeric). Indian J Clin Biochem 2001;16(2):153-60.

Okechukwu PN, Ndyeabura AW, Chiang CN, Akowuah GA. Effect of standardized extract of Cosinium fenestratum stem bark on liver and kidney function parameters in streptozotocin-induced diabetic rats. J Acute Dis 2013;2:201-6.

Azza A, El-Masry AA. Potential therapeutic effect of Curcuma longa on streptozotocin induced diabetic rats. Glob Adv Res J Med Med Sci 2012;1(4):91-8.

Sawant RS, Godghate AG. Qualitative phytochemical screening of rhizomes of Curcu ma longa Linn. Int J Environ Sci Technol 2013;2(4):634-41.

Brahmachari G. Bio-flavonoids with promising anti-diabetic potentials: A critical survey. Opportunity. Chall Scope Nat Prod Med Chem 2011;187-212.

Thiyagarajan R. Yugimuni Vaithya Chinthamani 800. 2nd ed. Chennai: Department of Indian Medicine and Homeopathy, Government of Tamil Nadu; 2005.

Thiyagarajan R. Gunapaadam Thadhu-Jeeva Vaguppu Part-2 and 3. 2nd ed. Chennai: Department of Indian Medicine and Homeopathy, Government of Tamil Nadu; 2006.

Akbar S, Hanif U, Ali J, Ishtiag S. Pharmacognostical studies of stem, roots and leaves of Malva parviflora L. Asian Pac J Trop Biomed 2014;4(5):410-5.

Lavanya B, Narayanan N, Maheshwaran A, Suganya S, Sree YS, Aravindan SV, et al. Basic anatomical and pharmacognostical study of Cassia fistula Linn (Caesalpiniaceae). Int J Pharm Biol Sci 2016;6(3):105-20.

WHO. Quality Control Methods for Medicinal Plant’s Materials. Geneva: World Health Organization; 1998.

Ugochukwu SC, Uche IA, Ifeanyi O. Preliminary phytochemical screening of different solvent extracts of stem bark and roots of Dennetia tripetala G. Baker. Asian J Plant Sci Res 2013;3(3):10-3.

Venugopal PM. Udal Thathuvam, Unavu Porulin Amsangal. 3rd ed. Chennai: Department of Indian Medicine and Homeopathy, Government of Tamil Nadu; 1993. p. 248-53.

Raja DK, Jeganathan NS, Manavalan R. In vitro antimicrobial activity and phytochemical analysis of Cassia auriculata Linn. Int Curr Pharm J 2013;2(6):105-8.

Murugan T, Wins JA, Murugan M. Antimicrobial activity and phytochemical constituents of leaf extracts of Cassia auriculata. Indian J Pharm Sci 2013;75(1):122-5.

Published

01-10-2017

How to Cite

Ks, U., P. P, and K. S. “PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL SCREENING OF AAVAARAI VIDHAI CHOORANAM”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 10, Oct. 2017, pp. 111-6, doi:10.22159/ajpcr.2017.v10i10.19422.

Issue

Section

Original Article(s)