ANTIOXIDANT ACTIVITY OF TARENNA POLYCARPA (MIQ.) KOORD. LEAF

Authors

  • Rika Puspita Sari Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
  • Marline Nainggolan Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
  • Rosidah Rosidah Department Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i4.21929

Keywords:

Antioxidant, Tarenna polycarpa, Leaf, Extract, Fractions

Abstract

 Objective: The objective of this study is to evaluate the antioxidant activity of Tarenna polycarpa (Miq.) koord. Ex Valenton. Leaf extract and fractions.

Methods: Antioxidant activity was examined by DPPH method.

Results: Ethanol extract, n-hexane fraction, and ethyl acetate fraction with DPPH assay measured as half maximal inhibitory concentration were 55.21, 109.73, and 42.04 μg/mL, respectively.

Conclusions: The results reveal that T. polycarpa extract and fractions have strong antioxidant potential. Our further study is to isolate compounds responsible for antioxidant components.

Downloads

Download data is not yet available.

References

Satria D, Silalahi J, Haro G, Ilyas S, Hsb PA. Antioxidant and antiproliferative activities of an ethylacetate fraction of picria fel-terrae lour. Herbs Asian Pac J Cancer Prev 2017;18:399-403.

Rosidah, Yam MF, Sadikun A, Asmawi MZ. Antioxidant potential of Gyunura procumbens. Pharm Biol 2008;46:616-25.

Hasibuan PA, Sitorus P, Satria D. Anticancer activity of β-sitosterol from Plectranthus amboinicus (Lour. Spreng.) leaves: In vitro and in silico studies. Asian J Pharm Clin Res 2017;10:306-8.

Jamuna S, Pulsamy S, Karthika K. Screening of in vitro antioxidant activity of methanolic leaf and root extracts of Hypochaeris radicata L. (Asteraceae). J Appl Pharm Sci 2012;2:149-54.

Nagmoti DM, Khatri DK, Juvekar PR, Juvekar AR. Antioxidant activity free radical-scavenging potential of Pithecellobium dulce Benth seed extracts. Free Radic Antioxid 2012;2:37-43.

Yang YC, Lu FH, Wu JS, Wu CH, Chang CJ. The protective effect of habitual tea consumption on hypertension. Arch Intern Med 2004;164:1534-40.

Anonim. (2016). Morbesi-bosi. (289614). [Last retrieved on 2016 May 19].

Kuntzeex SS, Anjanadevi N, Abirami P, dan Sharmila S. Antibacterial activity of leaf extract of Tarenna asiatica (L.). Indian J Microbiol Sci 2014;3:48-51.

Ramabharathi V. Phytochemical Investigation of the Gum Resin of Tarenna asiatica. Vol. 11. Dissertation. Tirupati (WU): Women University; 2011. p. 3-9.

Satria D, Furqan M, Hadisahputra S, Rosidah. combinational effects of ethylacetate extract of Picria fel-terrae Lour. and doxorubicin on T47D breast cancer cells. Int J Pharm Pharm Sci 2015;7:73-6.

Sitorus P, Satria D. Antibacterial activity of ethanol extract and volatile oil of laja gowah rhizome (Alpinia malaccensis Burm. F Roscoe.) against Staphylococcus aureus and Escherichia coli. Asian J Pharm Clin Res 2016;8:466-8.

Anggraeni R, Hadisahputra S, Silalahi J, Satria D. Combinational effects of ethylacetate extract of Zanthoxylum acanthopodium DC. With doxorubicin on T47D breast cancer cells. Int J PharmTech Res 2014;6:2032-5.

Hasibuan PA, Jessy C, Denny S. Combination effect of ethylacetate extracts of Plectranthus ambonicius (Lour.) Spreng. With doxorubicin againts T47D breast cancer cells. Int J Pharm Pharm Sci 2015;7:155-9.

Satria D, Pandapotan M, Illyas S. Cytotoxcicity effect of sea horse (Hippocampus trimaculatus Leach.) extract and fractions on MCF-7 cell line. Int J Pharmtech Res 2014;6:212-6.

Dalimunthe A, Achmad S, Satria D. Phenolic, flavonoid content and antioxidant activities of ethylacetate extract of Litsea cubeba (Lour.) Pers. Barks. Der Pharma Chem 2016;8:466-8.

Pan Y, Wang K, Huang S, Wang H, Mu X, He C, et al. Antioxidant activity of microwave-assisted extract of longan (Dimocarpus longum Lour.) peel. Food Chem 2008;106:1264-70.

Hasan SM, Hossain MM, Akter R, Jamila M, Mazumder ME, Rahman S. DPPH free radical scavenging activity of some Bangladeshi medicinal plants. J Med Plants Res 2009;3:875-9.

Koleva II, van Beek TA, Linssen JP, de Groot A, Evstatieva LN. Screening of plant extracts for antioxidant activity: A comparative study on three testing methods. Phytochem Anal 2002;13:8-17.

Meir S, Kanner J, Akiri B, Hada SP. Determination and involvement of aqueous reducing compounds in oxidative defense system of various senescing leaf. J Agric Food Chem 1995;43:1813-9.

Published

01-04-2018

How to Cite

Sari, R. P., M. Nainggolan, and R. Rosidah. “ANTIOXIDANT ACTIVITY OF TARENNA POLYCARPA (MIQ.) KOORD. LEAF”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 4, Apr. 2018, pp. 224-5, doi:10.22159/ajpcr.2018.v11i4.21929.

Issue

Section

Original Article(s)

Most read articles by the same author(s)

1 2 > >>