ACECLOFENAC-INDUCED STEVENS-JOHNSON SYNDROME AFTER ONE SINGLE DOSE: A MAIDEN CASE REPORT

Saurabh Agarwal; Balaji O; Navin Patil

doi:10.22159/ajpcr.2018.v11i9.24067

Authors

Saurabh Agarwal Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Balaji O Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Navin Patil Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i9.24067

Keywords:

Aceclofenac, Adverse drug reaction, Nil, Purpuric macules

Abstract

Drugs are known to cause various adverse drug reactions involving major organ systems. Skin-related adverse reactions are very common and range from a simple rash to life-threatening condition like Stevens-Johnson syndrome. Various drugs are known to cause skin reactions which include antiepileptics, analgesics, antibiotics, and proton-pump inhibitors. Nonsteroidal anti-inflammatory drugs causing life-threatening conditions such as Stevens-Johnson syndrome and toxic epidermal necrolysis are very rare and only few case reports are published. Hence, we report a case of Aceclofenac-induced Stevens-Johnson syndrome after single time administration in a tertiary care hospital in India.

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