SPILANTHES ACMELLA AND ITS MEDICINAL USES – A REVIEW
DOI:
https://doi.org/10.22159/ajpcr.2018.v11i6.24697Keywords:
Spilanthes acmella, Toothache plant, Antifungal, Antipyretic, Local anesthetic, Bioinsecticide, Antioxidant, Analgesic, Antimicrobial, Vasorelaxant, Anti-inflammatory effectsAbstract
ABSTRACT
In common plant life has been recognized to alleviate various diseases. Spilanthes acmella- a vital native medicinal plant, is also found in sub continent of America. A range of abstracts and active metabolites from different parts of this plant is found to contain valuable pharmacological activities. Traditionally recognized as tooth ache plant, it is known to suppress the ailment allied with tooth aches and is found to stimulate saliva secretion. On Survey of literatures it has been projected that, it has numerous drug related actions, which comprises of antimicrobial, antipyretic, local anaesthetic, bioinsecticide against insects of agricultural importance, antioxidant, analgesic, antimicrobial, vasorelaxant, anti-human immune deficit virus, tooth ache relief and anti-inflammatory effects. Based on the traditional claims against a range of diseases, researchers have classified and estimated plants for their bioactive compounds. However researchers found it to be a difficult task for the extraction of bioactive constituents from these plants. Therefore the scientific information about Spilanthes acmella could be obtained from this current review.
Â
Â
Downloads
References
Storey C, Salem JI. Lay use of Amazonian plants for the treatment of tuberculosis. Acta Amazonica 1997;27:175-82.
Sharma UK, Pegu S. Ethnobotany of religious and supernatural beliefs of the Mising tribes of Assam with special reference to the ’Dobur Uie’. J Ethnobiol Ethnomed 2011;7:1-13.
Chung KF, Kono Y, Wang CM, Peng CI. Notes on Acmella (Asteraceae): Helianthaceae in Taiwan. Bot Stud 2008;49:73-82.
Revathi P, Parimelazhghan T. Traditional knowledge on medicinal plants used by Irula tribe of Hasanur hills, Erode District, Tamil Nadu, India. Ethnobot Leaf 2010;14:136-60.
Vijendra N, Kumar KP. Traditional knowledge on ethno medicinal uses prevailing in tribal pockets of Chhindwara and Betul Districts, Madhya Pradesh, India. Afr J Pharm Pharmacol 2010;4:662-70.
Hossan MS, Hanif A, Agarwala B, Sarwar S, Karim M, Jahan R, et al. Traditional use of medicinal plants in Bangladesh to treat urinary tract infections and sexually transmitted diseases. Ethnobot Res Appl 2010;8:61-74.
Santesson CG. Several drugs of the Cameroon District and their native uses. Archi Furdie Bot A 1926;20:1-34.
Biswas A, Bari MA, Roy M, Bhadra SK. Inherited folk pharmaceutical knowledge of tribal people in the Chittagong hill tracts, Bangladesh. Indian J Tradit Knowl 2010;9:77-89.
Jondiko IJ. A mosquito larvicide in Spilanthes mauritiana. Phytochemistry 1986;25:2289-90.
Kadir HA, Zakaria MB, Kechil AA, Azirun MS. Toxicity and electrophysiological effects of Spilanthes acmella Murr. Pestic Sci 1989;25:329-35.
Mukharya DK, Ansari AH. Olean-12-en-3-O-beta-D-galactopyranosyl (1-4)-O-alpha-L-rhamnopyranoside: A new triterpenoidal saponin from the roots of Spilanthes. Indian J Chem Biol 1987;26:26-86.
Shelton AM, Wyman JA, Cushing NL, Apfelbeck K, Dennehy TJ, Mahr SE, et al. Insecticide resistance of diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae), in North America. J Econ Entomol 1993;86:11-9.
Shelton AM, Robertson JL, Tang JD, Perez C, Eigenbrode SD, Preisler HK, et al. Resistance of diamondback moth (Lepidoptera: Plutellidae) to Bacillus thuringiensis subspecies in the field. J Econ Entomol 1993;86:697-705.
Verma DM, Balakrishnana NP, Dixit RD. Flora of Madhya Pradesh. Vol. 1. Kolkata: Botanical Survey of India; 1993. p. 612-3.
Gokhale VG, Bhide BV. Chemical Investigation of Spilanthes acmella. J Indian Chem Soc 1945;22:250-2.
Prachayasittikul S, Suphapong S, Worachartcheewan A, Lawung R, Ruchirawat S, Prachayasittikul V. Bio- active Metabolites from Spilanthes acmella Murr. Molecules 2009;14:850-67.
Martin R, Becker H. Spilanthol-related amides from Acmella ciliate. Phytochemistry 1984;23:1781-83.
Martin R, Becker H. Amides and Other constituents from Acmella ciliate. Phytochemistry 1985;24:2295-300.
Broussalis AM, Ferraro GE, Martino VS, Pin-Zon R, Coussio JD, Alvarez JC. Argentine plants as potential source of insecticidal compounds. J Ethnopharmacol 1999;67:219-23.
Pandey V, Agrawal V, Raghavendra K, Dash AP. Strong insecticidal activity of three species of Spilanthes (Akarkara) against Malaria (Anopheles stephensi Liston, Anopheles culicifacies, species C) and Filaria Vector (Culex quinquefasciatus Say). Parasitol Res 2007;102:171-4.
Ramsewak RS, Erickson AJ, Nair MG. Bioactive N-isobutylamides from the flower buds of Spilanthes acmella. Phytochemistry 1999;51:729-32.
Okemo P, Ansorg R. Activity of east african medicinal plants against Helicobacter pylori. Chemother Basel 1996;42:315-7.
Rani SA, Murty SU. Evaluation of antimicrobial activity of Spilanthes acmella flower head extract. J Nat Remedies 2005;5:170-1.
Sharma GV, Shekharam T, Upender V. Stere- oconvergent synthesis of a potent mosquito larvicide: (2E,4E,8E,10Z)-N-(2-methylprpyl)-2,4,8,10-dodecatetraeneamide. Tetrahedron 1990;46:5665-72.
Fabry W, Okemo P, Ansorg R. Fungistatic and fungicidal activity of east African medicinal plants. Mycoses 1996;39:67-70.
Rai MK, Verma A, Pandey AK. Antifungal activity of Spilanthes calva after inoculation of Pirifor-maspora indica. Mycoses 2002;47:479-81.
Phongpaichit S, Subhadhirasakul S, Wattanapi-Romsakul C. Antifungal activities of extracts from Thai medicinal plants against opportunistic fungal pathogens associated with AIDS Patients. Mycoses 2005;48:333 8.
Rani SA, Murty SU. Antifungal potential of flower head extract of Spilanthes acmella Linn. Afr J Biomed Res 2006;9:67-8.
Okwu DE. Phytochemicals and vitamin content of indigenous species of southeastern Nigeria. J Sustain Agric Environ 2004;6:30-7.
Just MJ, Recio MC, Giner RM, Cueller MU, Manez S, Billia AR, et al. Antiinflammatory activity of unusual lupine saponins from Bupleurum fruticescens. Planta Med 1998;64:404-7.
Sodipo OA, Akiniyi JA, Ogunbamosu JU. Studies on certain on certain characteristics of extracts of bark of Pansinystalia macruceras (K schemp) picrre Exbeille. Glob J Pure Appl Sci 2000;6:83-7.
Raquel FE. Bacterial lipid composition and antimicrobial efficacy of cationic steroid coppounds. Biochem Biophys Acta 2007;1768:2500-9.
Okwu DE. Evaluation of chemical composition of medicinal plants belonging to Euphorbiaceae. Pak Vet J 2001;14:160-2.
Nobori T, Miurak K, Wu DJ, Takabayashik LA, Carson DA. Deletion of cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994;46:753-6.
Antherden LM. Textbook of Pharmaceutical Chemistry. 8th ed. London: Oxford University Press; 1969. p. 813-4.
Stray F. The Natural Guide to Medicinal Herbs and Plants. London: Tiger Books International; 1998. p. 12-6.
Okwu DE, Okwu ME. Chemical composition of Spondias mombin linn. Plant parts. J Sustain Agric Environ 2004;6:140-7.
Nyarko AA, Addy ME. Effects of aqueous extract of Adenia cissampeloides on blood pressure and serum analyte of hypertensive patients. Phytother Res 1990;4:25-8.
Ahmad I, Mehmood Z, Mohammad P, Ahmed S. Antimicrobial potency and synergistic activity of five traditionally used Indian medicinal plants. J Med Arom Plant Sci 2000;22:173-6.
Darokar MP, Mathur A, Dwivedi S, Bhalla R, Kanuja SP, Kumar S. Detection of antibacterial in the floral petals of some higher plants. Curr Sci 1998;75:187-9.
Fabry W, Okemo PO, Ausorg R. Antibacterial activity of east african medicinal plants. J Ethnopharmocol 1998;60:19-24.
Rajesh Y, Nita Y, Murli DK, Rudraprabhu S. Preliminary studies on diuretic effect of Spilanthes acmella leaves extracts in rats. Int J Pharm Pharm Sci 2011;3:245-7.
Sahaya S, Servin W, Devi BC. Antimicrobial activity of in vitro raised Acmella calva (DC.). Int J Pharm Pharm Sci 2012;4 Suppl 5;124-7.
Sharma J, Boonen NS, Chauhan M, Thakur B, De Spiegeleer B, Dixit VK. Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats. Phytomedicine 2011;18:1161-9.
Parekh J, Karathia N, Chanda S. Evaluation of antibacterial activity and phytochemical analysis of Bauhinia variegata L. Bark. Afr J Biomed Res 2006;9:53-6.
Remington JP. Remington: The Science and Practice of Pharmacy. 21st ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2005. p. 773-4.
Roopashree TS, Dang R, Rani SR, Narendra C. Antibacterial activity of anti- psoriatic herbs: Cassia tora, Momordica charantia and Calendula officinalis. Int J Appl Res Nat Prod 2008;1:20-8.
Sutar N, Garai R, Sharma US, Sharma UK. Anthelmintic activity of Platycladus orientalis leaves extract. Int J Parasitol Res 2010;2:1-3.
Sharma US, Sharma UK, Singh A, Sutar N, Singh PJ. In vitro anthelmintic activity of Murraya koenigii linn. Leaves extracts. Int J Pharm Biosci 2010;1:1-4.
Vidyadhar S, Saidulu M, Gopal TK, Chamundeeswari D, Rao U, Banji D. In vitro anthelmintic activity of the whole plant of Enicostemma littorale by using various extracts. Int J Appl Biol Pharm Technol 2010;1:1119-25.
Wallis TE. Text Book of Pharmacognosy. New Delhi: CBS Publishers and Distributors; 1989. p. 356-549.
Wang GX, Han J, Zhao LW, Jiang DX, Liu YT, Liu XL, et al. Anthelmintic activity of steroidal saponins from Paris polyphylla. Phytomedicine 2010;17:1102-5.
Wang GX, Zhou Z, Jiang DX, Han J, Wang JF, Zhao LW, et al. In vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim) fedde against dactylogyrus intermedius in Carassius auratus. Vet Parasitol 2010;171:305-13.
Eloff JN. Which extractant should be used for the screening and isolation of antimicrobial components from plants? J Ethnopharmacol 1998;60:1-8.
Evans WC. Treas and Evans Pharmacognosy.†14th ed. Edinburgh: WB Saunders Company Ltd.; 2002. p. 3-4.
Handa SS, Khanuja SP, Longo G, Rakesh DD. Extraction Technologies for Medicinal and Aromatic Plants. Trieste: International Centre for Science and High Technology; 2008. p. 21-5.
Johansen DA. Plant Micro Technique. New York: McGraw Hill Book Co.; 1940. p. 182-97.
Rai MK, Acharya D. Screening of some Asteraceous plants for antimycotic activity. Composit Newslett 1999;34:37-43.
Rai MK, Varma A, Pandey AK. Antifungal potential of Spilanthes calva after inoculation of Piriformospora indica. Mycoses 2004;47:479.
Published
How to Cite
Issue
Section
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.
