THE EFFECTS OF THE ADDUCTION OF EFFERVESCENT POWDER OF BASTARD CEDAR LEAF (GUAZUMA ULMIFOLIA LAMK.) EXTRACT TOWARD WEIGHT REDUCTION OF MALE MICE

Sumaiyah; Rizky Triandini; Aminah Dalimunthe

doi:10.22159/ajpcr.2018.v11s1.26604

Authors

Sumaiyah Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia
Rizky Triandini Department of Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Aminah Dalimunthe Department of Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11s1.26604

Keywords:

Effervescent powder, Guazuma ulmifolia Lamk, Extract, Weight reduction

Abstract

Â Objective: The objective of this study was to discover the effect of the adduction of Bastard cedar leaf extract that was formulated in the form of effervescent powder toward weight loss.

Methods: The study design was an experimental study with pretestâ€“posttest one group control design. The sample was divided into 3 treatment groups which were dosage 1 g/kg body weight (BW), 2 g/kg BW, and 3 g/kg BW of Bastard cedar leaf effervescent powder and one control group. The research was conducted for 28 days.

Result: The result of the research exhibited the 1st day of the adduction of Bastard cedar leaf effervescent powder that the dosage 3 g/Kg BW contributed to the largest reduction compared with the others. On the last day of adduction, dosage 1 g/Kg BW contributed almost the similar weight reduction effect to the mouse with the dosage 3 g/Kg BW; however, when both were compared, the dosage 3 g/Kg BW remained giving the most significant effect (p<0.05).

Conclusion: The adduction of bastard cedar leaf effervescent powder could reduce the weight of the mouse in all dosage treatment which was dosage 1 g/Kg BW, 2 g/Kg BW, and 3 g/Kg BW.

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