CORRELATION OF TYPE-2 DIABETES MELLITUS AND DYSLIPIDEMIA AMONG NEPALESE

Authors

  • Keshab Raj Joshi
  • Koushik Bhattacharya
  • Sanjit Kumar Kar
  • Prem Kumar Yadav
  • Sanjay Kuamr Sah
  • Sandeep Pokhrel

Abstract

 

 Objectives: More cardiovascular disease occurs in patients with either Type 1 diabetes mellitus (DM) or Type 2 DM (T2DM). Serum high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol profiles in T2DM is quite useful, as it may serve as a reliable monitor to judge the prognosis of the patients. The aim of the present study is to examine T2DM and dyslipidemia and their correlation in residents of Nepal. The detection of risk factors in the early stage of the disease will help the patients to improve and reduce the morbidity rate as LDL promotes cholesterol deposition in the arterial wall.

Methods: This case-control study was carried out in Lumbini Medical College, Palpa, Nepal, on total of 100 subjects, with 50 controls (non-diabetic cases) and 50 T2DM patients, to study their HDL and LDL profiles.

Results: The present study showed increased levels of fasting blood sugar (164.5 [51.17] than in control 95.4 [10.09]) and LDL cholesterol (121.4 [27.89] than in control 103.6 [30.67]) in T2DM subjects; conversely, serum HDL cholesterol (39.2 [7.96]) level was reduced significantly in T2DM patients (than in controls 44.0 [10.57]).

Conclusion: Thus, the findings of the present study imply a significant correlation between serum HDL and LDL cholesterols in T2DM subjects.

Keywords: Blood glucose, Cholesterol, High density lipoprotein, Low density lipoprotein, Non-insulin dependent diabetes mellitus

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References

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Published

01-11-2014

How to Cite

Joshi, K. R., K. Bhattacharya, S. K. Kar, P. K. Yadav, S. K. Sah, and S. Pokhrel. “CORRELATION OF TYPE-2 DIABETES MELLITUS AND DYSLIPIDEMIA AMONG NEPALESE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 7, no. 5, Nov. 2014, pp. 295-9, https://mail.innovareacademics.in/journals/index.php/ajpcr/article/view/2681.

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