MEASUREMENT OF ADJUSTED ISCHEMIA-MODIFIED ALBUMIN MARKER IN EARLY PREGNANCY LOSS

MIAMI ABD-AL HASAN; RIHAB ABD UL-MALIK; ISRAA TALIB ABD AL KADIR

doi:10.22159/ajpcr.2020.v13i3.35546

Authors

MIAMI ABD-AL HASAN Department of Obstetrics and Gynecology, College of Medicine, Al-Mustansiriya University, AL-Yarmouk Teaching Hospital, Baghdad, Iraq. http://orcid.org/0000-0001-5063-4667
RIHAB ABD UL-MALIK Department of Obstetrics and Gynecology, Al-Yarmouk Teaching Hospital, Baghdad, Iraq. http://orcid.org/0000-0002-7681-6829
ISRAA TALIB ABD AL KADIR Department of Obstetrics and Gynecology, Al-Yarmouk Teaching Hospital, Baghdad, Iraq. http://orcid.org/0000-0001-9242-3147

DOI:

https://doi.org/10.22159/ajpcr.2020.v13i3.35546

Keywords:

Pregnancy loss, Pregnant women, Adjusted ischemia-modified albumin marker

Abstract

Objective: The objective of the study was to identify the possible association between adjusted ischemia-modified albumin (IMA) marker and early pregnancy loss.

Study Design: This was a case–control study.

Setting: This study was conducted at the Department of Obstetrics and Gynecology of Al-Yarmouk Teaching Hospital.

Methods: The study included 90 pregnant women, aged from 18 to 35 years old, attending the outpatient and inpatient clinic with single fetal pregnancy with a gestational age range between 6th and 12th weeks, they were divided into two groups; Group A included 45 cases with single viable fetus – control group. Group B included 45 cases diagnosed as missed miscarriages at time of enrollment – study group. Serum IMA was measured for patients in both groups.

Results: Adjusted IMA levels increased in normal pregnancy, but it was higher in woman with early pregnancy loss. Cutoff 41.2 ng/mL was used to discriminate between normal pregnancy and early pregnancy loss, with a sensitivity 0.77, specificity 0.51, and accuracy 0.64.

Conclusion: IMA and adjusted IMA levels were elevated in women with early pregnancy loss.

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Author Biographies

MIAMI ABD-AL HASAN, Department of Obstetrics and Gynecology, College of Medicine, Al-Mustansiriya University, AL-Yarmouk Teaching Hospital, Baghdad, Iraq.

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RIHAB ABD UL-MALIK, Department of Obstetrics and Gynecology, Al-Yarmouk Teaching Hospital, Baghdad, Iraq.

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ISRAA TALIB ABD AL KADIR, Department of Obstetrics and Gynecology, Al-Yarmouk Teaching Hospital, Baghdad, Iraq.

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