MEDICINAL PLANTS FOR DIABETES MELLITUS: A REVIEW
DOI:
https://doi.org/10.22159/ajpcr.2021.v14i4.40825Keywords:
Diabetes mellitus, Ayurveda, Medicinal plants, HypoglycemicAbstract
Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Fourth leading causes of death in the most advanced countries and there, in other emerging and recently industrialized nations, still controlled the epidemic. Inadequate control of blood sugar has significant consequences for well-being. Ayurveda and other Indian writing referenced the utilized of plants in the treatment of different diseases. Medicinal plant with antidiabetic potential has been recent area of research. The efficiency of these medicinal plants may regulate the diabetic metabolic abnormalities. This work would help researchers to choose potential herbal for diabetic treatment.
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Mungle A, Bodhankar M, Chandak K. Antidiabetic potential of Dolichandrone falcata leaves in alloxan induced diabetic rats. Int J Res Pharm Biomed Sci 2012;3:319-24.
Ahangarpour A, Mohammadian M, Dianat M. Antidiabetic effect of hydroalcholic Urtica dioica leaf extract in male rats with fructose-induced insulin resistance. Iran J Med Sci 2012;37:181-6.
Lehninger AL, Nelson DL. MM Cox. Principle of Biochemistry. New York: Worth Publishers; 2010.
Alarcon-Aguilara FJ, Roman-Ramos R, Perez-Gutierrez S, Aguilar- Contreras A, Contreras-Weber CC, Flores-Saenz JL. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10.
Anand KK, Singh B, Grand D, Chandan BK, Gupta VN. Effect of Zizyphus sativa leaves on blood glucose levels in normal and alloxan-induced diabetic rats. J Ethnopharmacol 1989;27:121-7.
Arambewela LS, Arawwawala LD, Ratnasooriya WD. Antidiabetic activities of aqueous and ethanolic extracts of Piper betle leaves in rats. J Ethnopharmacol 2005;102:239-45.
Arokiyaraj S, Balamurugan R. Antihyperglycemic effect of Hypericum perforatum ethyl acetate extract on streptozotocin-induced diabetic rats. Asian Pac J Trop Biomed 2011;1:386-90.
Cakici I, Hurmoglu C. Hypoglycemic effects of Momordica charantia extract in normoglycaemic or cyproheptadin induced hyperglycaemic mice. J Ethnopharmacol 1994;44:117-22.
Cetto AA, Wiedenfeld H. Anti-hyperglycemic effect of Opuntia streptacantha Lem. J Ethnopharmacol 2011;133:940-3.
Kumar D, Kumar S, Kohli S, Arya R, Gupta J. Antidiabetic activity of methanolic bark extract of Albizia odoratissima Benth. in alloxan induced diabetic albino mice. Asian Pac J Trop Med 2011;4:900-3.
Edem DO. Hypoglycemic effects of ethanolic extracts of Persea americana Mill seed (Alligator Pear.) in rats. Eur J Sci Res 2009;33:669-78.
Eidi A, Eidi M, Darzi R. Antidiabetic effect of Olea europaea L. in normal and diabetic rats. Phytother Res 2009;23:347-50.
Eliza J, Diasy P, Ignacimuthu S, Duraipandiyan V. Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.) Sm., in STZ-induced diabetic rats. Chem Biol Interact 2009;182:67-72.
Farzaneh V, Carvalho IS. A review of the health benefit potentials of herbal plant infusions and their mechanism of actions. Ind Crops Prod 2015;65:247-58.
Grover JK, Vats V, Rathi SS. Antihyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzyme involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70.
Hannan JMA, Marenah L, Ali L, Rokeya B, Flatt PR, Abdel-Wahab YH. Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic ß-cells. J Endocrinol 2006;189:127-36.
Hou SZ, Chen SX, Huang S, Jiang DX, Zhou CJ, Chen CQ, et al. The hypoglycemic activity of Lithocarpus polystachyus Rehd. leaves in the experimental hyperglycemic rats. J Ethnopharmacol 2011;138:142-9.
Huang CS, Yin MC, Chiu LC. Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats. Food Chem Toxicol 2011;41:2189-95.
Jafri MA, Aslam M, Javed K, Singh S. Effect of Punica granatum Linn (flowers) on blood glucose level in normal and alloxan-induced diabetic rats. J Ethnopharmacol 2000;70:309-14.
Jianfang F, Jufang F, Jun Y, Zhang N, Gao B, Fu G, et al. Anti-Diabetic activities of Acanthopanax senticosus polysaccharide (ASP) in combination with metformin. Int J Biol Macromol 2012;50:619-23.
Kamtchouing P, Kahpui SM, Djomeni Dzeufiet PD, Tédong L, Asongalem EA, Dimo T. Anti-diabetic activity of methanol/ methylene chloride stem bark extracts of Terminalia superba and Canarium schweinfurthii on streptozotocin-induced diabetic rats. J Ethnopharmacol 2005;104:306-9.
Khan IA, Khanum A. Modern and Alternative Medicine for Diabetes. Hyderabad, India: Ukaaz Publication; 2005.
Kumar GP, Arunselvan P, Kumar DS, Subramanian P. Anti-diabetic activity of fruits of Terminalia chebula on streptozotocin-induced diabetic rats. J Health Sci 2006;52:283-91.
Kumar S, Kumar V, Prakash O. Antidiabetic, hypolipidemic and histopathological analysis of Dillenia indica (L.) leaves extract on alloxan induced diabetic rats. Asian Pac J Trop Med 2011;4:347-52.
Macharla SP, Goli V, Sattla SR. Antidiabetic activity of Rephanus sativus L, leaves extracts on alloxan induced diabetic rats. J Chem Pharm Res 2012;4:1519-22.
Medjdoub H, Tabti B, Baatouche M, Baou L, Zehhaf S, Azzeddine K. Antihyperglycemic effect of Zygophyllum geslini aqueous extract in streptozotocin-induced diabetic wistar rats. J Life Sci 2012;6:652-6.
Meliani N, Amine Dib ME, Allali H, Tabti B. Hypoglycaemic effect of Berberis vulgaris L. in normal and streptozotocin induced diabetic rats. Asian Pac J Trop Biomed 2011;6:468-71.
Mentreddy SR, Mohamed AI, Rimando AM. The Alzheimer’s Association International Conference; 2005. p. 341-53.
Mohan Y, Jesuthankaraj GN, Thangavelu NR. Antidiabetic and antioxidant properties of Triticum aestivum in streptozotocin-induced diabetic rats. Adv Pharmacol Sci 2013;2013:716073.
Mukherjee PK, Saha K, Pal M, Saha BP. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol 1997;58:207-13.
Narendiran S, Mohanambal E. Study of anti-diabetic and anti-oxidant activities of methanolic extract of Xanthium strumarium (Linn.) stems on diabetic rats. J Pharm Res 2011;4:3728-32.
Ojewole JA. Antinociceptive, anti-inflammatory and antidiabetic effects of Bryophyllum pinnatum (Crassulaceae) leaf aqueous extract. J Ethnopharmacol 2005;99:13-9.
Ozolua RI, Eriyamremu GE, Okene EO, Ochei U. Hypoglycemic effects of viscous preparation of Irvingia gabonensis (Dikanut) seeds in streptozotocin induced diabetic wistar rats. J Herb Spices Med Plants 2006;12:1-9.
Pandey J, Maurya R, Raykhera R, Srivastava MN, Yadav PP, Tamrakar AK. Murraya koenigii (L.) spreng. ameliorates insulin resistance in dexamethasone-treated mice by enhancing peripheral insulin sensitivity. J Sci Food Agric 2014;94:2282-8.
Peunqvicha P, Thirawarapan SS, Watanabe H. Hypoglycemic effect of water extract of the root of Pandanus odorus RIDL. Biol Pharm Bull 1996;19:364-6.
Ponnusamy S, Ravindran R, Zinjarde S, Bhargava S, Kumar AR.Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro. Evid Based Complement Alternat Med 2011;2011:515647.
Prisilla DH, Balamurugan R, Shah HR. Antidiabetic activity of methanol extract of Acorus calamus in STZ induced diabetic rats. Asian Pac J Trop Biomed 2012;2:S941-6.
Kumar R, Pate DK, Prasad SK, Sairam K, Hemalatha S. Antidiabetic activity of alcoholic leaves extract of Alangium lamarckii Thwaites on streptozotocin-nicotinamide induced Type 2 diabetic rats. Asian Pac J Trop Med 2011;4:904-9.
Joshi RK, Setzer WN, Veiga VF Jr. Aromatic and medicinal plants with anti-diabetic potential from India: A review. Am J Essent Oils Nat Prod 2015;2:24.
Ravi K, Ramachandran B. Effect of Eugenia jambolana seed kernel on antioxidant defense system in streptozotocin induced diabetes in rats. Life Sci 2004;75:2717-31.
Roman-Ramos R, Flores-Saenz JL, Alarcon-Aguilar FJ. Anti-hyperglycemic effect of some edible plants. J Ethnopharmacol 1995;48:25-32.
Saravanan G, Pari L. Hypoglycaemic and antihyperglycaemic effect of Syzygium cumini bark in streptozotocin-induced diabetic rats. J Pharmacol Toxicol 2008;3:1-10.
Sefi M, Fetoui H, Lachkar N, Tahraoui A, Lyoussi B, Boudawara T, et al. Centaurium erythrea (Gentianaceae) leaf extract alleviates streptozotocin-induced oxidative stress and β-cell damage in rat pancreas. J Ethnopharmacol 2011;135:243-50.
Sendogdu N, Aslan M. Antidiabetic and antioxidant effects of Vitis vinifera L. leaves in streptozotocin-diabetic rats. Turk J Pharm Sci 2006;3:7-18.
Sharma V, Marwaha A. Hypoglycemic activity of methanolic extracts of Nyctanthes arbor-tristis Linn. root in alloxan induced diabetic rats. Int J Pharm Pharm Sci 2011;3:210-2.
Somani RS, Singhai AK. Hypoglycaemic and antidiabetic activities of seeds of Myristica fragrans in normoglycaemic and alloxan-induced diabetic rats. Asian J Exp Sci 2008;22:95-102.
Suman RK, Borde MK. Antidiabetic activity of Gymnema sylvestre leaves extract on streptozocin induced experimental diabetic rats. Indo Am J Pharm Res 2015;5:2054-60.
Winarno H. The effect of Inai (Lawsonia inermis) leaves extract on blood glucose level: An experimental study. Res J Pharmacol 2008;2:20-3.
Teimori M, Montasser KS. Study of hypoglycemic effect of Juglans regia leaves and its mechanism. J Med Plants 2010;9:57-65.
Tshibangu PT, Kapepula PM, Kapinga MJ, Mukuta AT, Kalenda DT, Tchinda AT, et al. Antiplasmodial activity of Heinsia crinita (Rubiaceae) and identification of new iridoids. J Ethnopharmacol 2017;196:261-6.
Udayakumar R, Kasthurirengan S, Mariashibu TS, Rajesh M, Anbazhagan VR, Kim SC, et al. Hypoglycaemic and hypolipidaemic effects of Withania somnifera root and leaf extracts on alloxan-induced diabetic rats. Int J Mol Sci 2009;10:2367-82.
Vikrant A, Sharma R. A review on fruits having anti-diabetic potential. J Chem Pharm Res 2011;3:204-12.
Wani TA, Pandith SA, Rana S, Bhat WW, Dhar N, Razdan S, et al. Promiscuous breeding behaviour in relation to reproductive success in Grewia asiatica L. (Malvaceae). Flora Morphol Distribut Funct Ecol Plants 2015;211:62-71.
Yoshino K, Miyauchi Y, Kanetaka T, Takagi Y, Koga K. Anti-diabetic activity of a leaf extract prepared from Salacia reticulata in mice. Biosci Biotechnol Biochem 2009;73:1096-104.
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