A COMPARATIVE STUDY OF SAFETY AND EFFICACY OF 30% FORMIC ACID WITH 85% FORMIC ACID IN THE TREATMENT OF PALMOPLANTAR WARTS.

Authors

  • Deepti C Dsouza Father Muller Medical College
  • Neema M Ali

Abstract

 

Objective: Warts are a common skin disease seen by dermatologists. It is an infection caused by different strains of human papilloma virus. The
presence of various topical and systemic treatments for warts is a testament to the lack of a rapid, simple, uniformly effective, inexpensive, nonscarring,
and painless treatment. The purpose of this study was to compare the safety and efficacy of 85% formic acid with 30% formic acid on
palmoplantar warts.
Methods: A non-randomized, open trial was performed in 30 patients with common warts attending Father Muller's Medical College Hospital,
Mangalore. 15 patients received 85% formic acid application, and 15 patients received 30% formic acid using a to puncture technique every
day.
Results: About 73.3% in Group I and 73.3% in Group II showed disappearance of warts at the end of 3 months. No major side-effects were seen at the
end of therapy in either group.
Conclusions: The results show that both 30% and 85% formic acid application are a safe, economical, and effective alternative in the treatment of
common warts with few side-effects and 30% formic acid may be an effective replacement of 85% formic acid. A study with more number of patients
is needed to see the efficacy of this treatment.
Keywords: Warts, Formic acid, Palmoplantar warts.

Downloads

Download data is not yet available.

Author Biography

Deepti C Dsouza, Father Muller Medical College

Dermatology Department

Resident

References

Plasencia JM. Cutaneous warts: Diagnosis and treatment. Prim Care 2000;27(2):423-34.

Jaiswal AK, Singh G. Pattern of skin diseases in Kashmir region of India. Indian J Dermatol Venereol Leprol 1999;65(6):258-60.

Nair PS, Nair TG. Pattern of dermatological diseases in Trivandrum. Indian J Dermatol Venereol Leprol 1999;65(6):261-3.

Bhat RM, Vidya K, Kamath G. Topical formic acid puncture technique for the treatment of common warts. Int J Dermatol 2001;40(6):415-9.

Rao DS, Modithaya BS, Gonsalves RA. Carboxylic acids. In: Rao DS, editor. Chemistry. Mangalore: Deepa; 1998. p. 330-50.

Reynolds EF, Martindale. Formic acid. In: The Extra Pharmacopoeia. 31st ed. London: Royal Pharmaceutical Society; 1996. p. 1707.

Kuykendall-Ivy TD, Johnson SM. Evidence-based review of management of nongenital cutaneous warts. Cutis 2003;71(3):213-22.

Sterling JC, Handfield-Jones S, Hudson PM, British Association of Dermatologists. Guidelines for the management of cutaneous warts. Br J Dermatol 2001;144(1):4-11.

Gibbs S, Harvey I, Sterling J, Stark R. Local treatments for cutaneouswarts: Systematic review. BMJ 2002;325(7362):461.

Bourke JF, Berth-Jones J, Hutchinson PE. Cryotherapy of common viral warts at intervals of 1, 2 and 3 weeks. Br J Dermatol 1995;132(3):433‑6.

Johnson SM, Brodell RT. Treating warts: A review of therapeutic options. Consultant 1999;39:253-66.

Defelice RN, Rumsfield J, Bernstein JE, Roshal JY. Clinical evaluation of an after pediculocide nit removal system. Int J Dermatol 1989;28(7):468-70.

Goldfarb MT, Gupta AK, Gupta MA, Sawchuk WS. Office therapy for human papillomavirus infection in nongenital sites. Dermatol Clin 1991;9(2):287-96.

Luciano CS. Verruca plantaris: A compendium of its understanding and treatment. J Am Podiatry Assoc 1977;67(12):858-69.

Tagami H, Ogino A, Takigawa M, Imamura S, Ofuji S. Regression of plane warts following spontaneous inflammation. An histopathological study. Br J Dermatol 1974;90(2):147-54.

Published

01-03-2015

How to Cite

Dsouza, D. C., and N. M Ali. “A COMPARATIVE STUDY OF SAFETY AND EFFICACY OF 30% FORMIC ACID WITH 85% FORMIC ACID IN THE TREATMENT OF PALMOPLANTAR WARTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 8, no. 2, Mar. 2015, pp. 167-70, https://mail.innovareacademics.in/journals/index.php/ajpcr/article/view/4370.

Issue

Section

Original Article(s)