A COMPARATIVE STUDY OF DEXMEDETOMIDINE AND CLONIDINE AS AN ADJUVANT TO ROPIVACAINE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK

NAGALINGAM NATARAJAN; GOPALAKRISHNAN KUPPUSAMY; AISHWARYA RAMANATHAN; SMITUL DAVE

doi:10.22159/ajpcr.2022.v15i2.43752

Authors

NAGALINGAM NATARAJAN Department of Anaesthesiology, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India.
GOPALAKRISHNAN KUPPUSAMY Department of Anaesthesiology, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India.
AISHWARYA RAMANATHAN Department of Anaesthesiology, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India.
SMITUL DAVE Department of Anaesthesiology, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i2.43752

Keywords:

Supraclavicular brachial plexus block, Dexmedetomidine, Clonidine, Ropivacaine, postoperative analgesia

Abstract

Objectives: Ultrasound-guided supraclavicular brachial plexus block is the most commonly performed approach for the upper limb surgeries and perioperative pain relief. This study was conducted to compare the post-operative analgesic efficacy of dexmedetomidine and clonidine as an adjuvant to ropivacaine in supraclavicular brachial plexus block in patients undergoing upper limb surgeries.

Methods: This was a prospective, randomized, and double-blinded comparative research that included 60 ASA PS I and II patients who were scheduled for the upper limb surgery. The patients were randomized into two groups, namely, Group C and Group D, with 30 patients each. The patients in Group D were given USG-guided supraclavicular brachial plexus block with 30 ml of 0.5% ropivacaine and dexmedetomidine 1 μg/kg and patients in Group C received 30 ml of 0.5% ropivacaine and clonidine 1 μg/kg. The patients were monitored for post-operative and interpreted by visual analog score and duration of analgesia. The Student’s independent t-test was employed for comparing continuous variables. Chi-square test or Fisher’s exact test, whichever is appropriate, was applied for comparing categorical variables.

Results: The mean duration of analgesia was longer and the mean consumption of rescue analgesics was lower in Group D as compared to Group C. No significant post-operative complications or local side effects related to the block were noted.

Conclusion: Dexmedetomidine prolongs the duration of sensory and motor block as well as the duration of post-operative analgesia as compared to clonidine when used as an adjuvant to ropivacaine in supraclavicular brachial plexus block.

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