CORRELATING BIOCHEMICAL AND HEMATOLOGICAL PARAMETERS IN PATIENTS WITH DENGUE

ASHWINI MANISH JANTIKAR

doi:10.22159/ajpcr.2022.v15i10.45451

Authors

ASHWINI MANISH JANTIKAR Department of Biochemistry, American International Institute of Medical Sciences, Udaipur, Rajasthan, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i10.45451

Keywords:

biochemical parameters, hematological parameters, liver profile, dengue

Abstract

Objectives: The objectives of this study were to ascertain the correlation of the various biochemical and hematological parameters to dengue positive status.

Methods: Based on review of literature, we calculated the correlation of biochemical and hematological parameters of liver profile in dengue positive and dengue negative patients in a convenience sampling of 140 dengue negative and 49 dengue positive cases.

Results: Total bilirubin (TBI), total plasma protein, globulin, and alkaline phosphatase showed inverse correlation to dengue positive status, while albumin/globulin ratio elicited direct correlation. (p˂0.05) Other parameters, namely, random blood sugar, direct bilirubin, indirect bilirubin, albumin, SGPT, and SGOT showed no clear cut correlation with dengue positive or negative status (p>0.05).

Conclusions: TBI, total plasma protein, globulin and alkaline phosphatase, and albumin/globulin ratio should be ascertained in a large equal group-size randomized study to establish their authenticity as prognosticators of the disease.

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Author Biography

ASHWINI MANISH JANTIKAR, Department of Biochemistry, American International Institute of Medical Sciences, Udaipur, Rajasthan, India.

Associate Professor, Department of Biochemistry

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