STUDY OF VITAMIN D LEVELS IN EPILEPTIC CHILDREN IN AGE GROUP OF 2-16 YEARS
Abstract
ÂObjective: Epilepsy is a common neurological disorder in childhood. A number of medications are used in the treatment of epilepsy. Antiepileptic
drugs (AEDs) are known to exert deleterious effects on vitamin D metabolism. Its deficiency state in epileptics can lead to difficult seizure control as
vitamin D is said to have anti-epileptogenic activity in addition to its known role in calcium metabolism. Correction of vitamin D deficiency may help
in decreasing the morbidity as well as seizure frequency. The purpose of this prospective observational study was to determine vitamin D status in
these children.
Methods: Seventy children aged 2-16 years with epilepsy on AEDs were assessed for vitamin D levels.
Results: The results showed that the vitamin D levels in this study population were significantly low.
Conclusion: Vitamin D levels were significantly low in children with epilepsy and hence, it is recommended that vitamin D supplementation in these
children is necessary to reduce the seizure frequency and vitamin D deficiency related morbidity.
Keywords: 25OH vitamin D, Epilepsy, Antiepileptic drugs
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References
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