ORGANISMS CAUSING OSTEOMYELITIS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN AMONG PATIENTS SEEKING CARE ATA TERTIARY CARE ORTHOPEDIC CENTER

Authors

  • Rohit Jhamnani Department of Orthopaedics, 167 Military Hospital, Pathankot, Punjab, India.
  • Aakansha Gupta Index Medical College, Hospital and Research Center, Indore, Madhya Pradesh, India.
  • Divya Verma Department of Ophthalmology, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i4.46799

Keywords:

Osteomyelitis, Antimicrobial susceptibility, Culture

Abstract

Objective: The objective of this study was to study the organisms causing osteomyelitis and their antimicrobial susceptibility pattern from a tertiary care teaching hospital located in a region of Madhya Pradesh.

Methods: Fifty clinically diagnosed cases of osteomyelitis visiting the medical college and seeking care for the same in orthopedics department during the study period formed the study population. Pus samples were collected and sent to microbiology laboratory for culture and testing of their antimicrobial susceptibility as per the standard guidelines.

Results: Out of 50 water samples gathered, 25, 14, and 11 samples of water were gathered from municipal tap water, government hand pump, and water cooler separately. Close to half of the examples were viewed as inadmissible. Escherichia coli was viewed as answerable for 26% of tests while Pseudomonas in 1/5th of gathered examples. Staphylococcus aureus, 14 (87.5%) were found resistant to Penicillin-G. Pseudomonas aeruginosa, 14 (100%) were found resistant to ampicillin, whereas more than half cases were found be resistant to antibiotics, namely, ciprofloxacin, ofloxacin, and cephotaxime, respectively.

Conclusion: We observed changes in the patterns of isolated organisms and the establishment of higher levels of antibiotic resistance among bacterial isolates in osteomyelitis cases. It is imperative that monitoring be prioritized to track etiological changes and to adhere to a single health policy to stop the multidrug-resistant bacteria threat.

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Author Biographies

Rohit Jhamnani, Department of Orthopaedics, 167 Military Hospital, Pathankot, Punjab, India.

Assistant Professor, Department of Orthopaedics

Aakansha Gupta, Index Medical College, Hospital and Research Center, Indore, Madhya Pradesh, India.

Phd Scholar, Department of Microbiology

Divya Verma, Department of Ophthalmology, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India.

Associate Professor, Department of Ophthalmology

References

Collee JG, Dugaid JP, Fraser AG, Marmion BP, Simmons A, editors. Laboratory strategy in the diagnosis of infective syndromes. In: Mackie and McCartney Practical Medical Microbiology. 14th ed., Vol. 1. Delhi: Churchill Livingstone; 2012. p. 53-94.

Romanò CL, Romanò D, Logoluso N, Drago L. Bone and joint infections in adults: A comprehensive classification proposal. Eur Orthop Traumatol 2011;1:207-17. doi: 10.1007/s12570-011-0056-8, PMID 21837262

Vijayakumar AB, Reddy VP, Suphala B, Gopalakrishnan A, VinodKumar CS. A retrospective study of colorectal carcinoma in Central India. Int Surg J 2021;8:910-4.

Carvalho VC, Oliveira PR, Dal-Paz K, Paula AP, Félix Cda S, Lima AL. Gram-negative osteomyelitis: Clinical and microbiological profile. Braz J Infect Dis 2012;16:63-7. doi: 10.1016/S1413-8670(12)70276-3, PMID 22358358

Reza M, Shahab F, Jalal K, Farhad J, Khoobdel M, Jonaidi N, et al. Epidemic assessment of bacterial agents in osteomyelitis and their antibiotic resistance pattern determination. J Biol Sci 2008;8:478-81.

Forbes BA, Sahm DF, Weissfeld AS. Baily and Scott’s Diagnostic Microbiology. 12th ed. United States: Mosby Inc; 2007.

Collee JG, Miles RS, Watt B. Tests for the identification of bacteria. In: Collee JG, Fraser AG, Marmion BP, Simmons A, editors. Mackie and McCartney Practical Medical Microbiology. 14th ed. Edinburgh: Churchill Livingstone; 2006. p. 131-49.

Clinical Laboratory Standards Institutes. Performance Standards for Antimicrobial Susceptibility Testing, XXI International Supplement (M100-S21). Wayne, PA: National Commit Clinic Laboratory Standards Institutes; 2016.

Faúndez G, Troncoso M, Navarrete P, Figueroa G. Antimicrobial activity of copper surfaces against suspensions of Salmonella enterica and Campylobacter jejuni. BMC Microbiol 2004;4:19. doi: 10.1186/1471-2180-4-19, PMID 15119960

Bureau of Indian Standards. Drinking Water Specification. 1st rev. New Delhi: Bureau of Indian Standards; 1991. p. 1-8.

Anstiss RG, Ahmed M. A conceptual model to be used for community-based drinking water improvements. J Health Popul Nutr 2006;24:262- 6. PMID 17366766

Wadekar MD, Anuradha K, Venkatesha D. Chronic osteomyelitis: Aetiology and antibiotic susceptibility pattern. Int J Rec Trends Sci Technol 2014;9:337-40.

Kaur J, Gulati VL, Aggarwal A, Gupta V. Bacteriological profile of osteomyelitis with special reference to Staphylococcus aureus. Int J Pract Doc 2008;4:1-2.

Sheehy SH, Atkins BA, Bejon P, Byren I, Wyllie D, Athanasou NA, et al. The microbiology of chronic osteomyelitis: Prevalence of resistance to common empirical anti-microbial regimens. J Infect 2010;60:338-43. doi: 10.1016/j.jinf.2010.03.006, PMID 20230854

Published

07-04-2023

How to Cite

Jhamnani, R., A. Gupta, and D. Verma. “ORGANISMS CAUSING OSTEOMYELITIS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN AMONG PATIENTS SEEKING CARE ATA TERTIARY CARE ORTHOPEDIC CENTER”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 4, Apr. 2023, pp. 54-56, doi:10.22159/ajpcr.2023.v16i4.46799.

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