EVALUATION OF SERUM AND SALIVARY CA-125 IN BREAST CANCER PATIENTS – AN ANALYTICAL STUDY

Authors

  • URVASHEE DWIVEDI Blood Bank, Government Medical College, Jalaun, Uttar Pradesh, India.
  • ANURAG JAIN Department of Surgery, Government Medical College, Ratlam, Madhya Pradesh, India.
  • FATIMA BHOPALWALA ALI Department of Anatomy, Government Medical College, Ratlam, Madhya Pradesh, India. https://orcid.org/0000-0003-1700-7850
  • Mustafa Ali Department of Pathology, Government Medical College, Ratlam, Madhya Pradesh, India. https://orcid.org/0000-0001-5664-8840

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i4.46864

Keywords:

Cancer antigen 125, Breast cancer, Enzyme-linked immunosorbent assay, Tumor markers

Abstract

Objective: Breast cancer in females is very frequent nowadays both in developed and developing countries. Many tests both invasive and non-invasive are available for the diagnosis of cancer breast. Tumor markers are the substances that are associated with tumors and help in the detection and follow-up. Cancer antigen 125 (CA-125) is one of the tumor markers, the level of which increases in many tumors including breast cancer.

Methods: The present study was carried out to quantitatively measure its level by enzyme-linked immunosorbent assay in the serum and saliva of known breast cancer patients and comparing it with control groups.

Results: Statistically significant role of CA-125 in cases of breast cancer was ascertained over the control group and also positive correlation was found between serum and salivary values of CA-125.

Conclusion: We conclude that CA-125 can be used as tumor markers in breast cancer patients for evaluation and salivary samples are equally effective as serum samples and also are easy and safe to obtain.

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References

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Published

07-04-2023

How to Cite

DWIVEDI, U., A. JAIN, F. B. ALI, and M. Ali. “EVALUATION OF SERUM AND SALIVARY CA-125 IN BREAST CANCER PATIENTS – AN ANALYTICAL STUDY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 4, Apr. 2023, pp. 97-99, doi:10.22159/ajpcr.2023.v16i4.46864.

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