BICKERSTAFF BRAINSTEM ENCEPHALITIS AND MILLER FISHER SYNDROME – VARIANT OF GUILLAIN-BARRÉ SYNDROME A SPECTRUM OF CLINICAL MANIFESTATION OF SAME DISEASE

Authors

  • MANISH KULSHRESTHA Department of Medicine, Ananta Institute of Medical Sciences and Research Center, Rajsamand, Rajasthan, India.
  • ANJALI KULSHRESTHA Department of Microbiology, Ananta Institute of Medical Sciences and Research Center, Rajsamand, Rajasthan, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i2.47372

Keywords:

Guillain-Barré syndrome, Miller Fisher syndrome, Parainfectious neurological illness

Abstract

Guillain-Barré syndrome (GBS) and its variants are parainfectious (2/3 cases) neurological illness involving the lower motor neuron but they can also involve central nervous system (CNS). Bickerstaff brainstem encephalitis (BBE) and Miller Fisher syndrome (MFS) are the two variants of GBS with CNS involvement. The present case series highlights the variable presentation and laboratory findings in BBE and MFS, which may help clinicians in early recognition and timely management of the condition.

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References

Van Doorn PA, Ruts L, Jacobs BC. Clinical features, pathogenesis, and treatment of Guillain-Barré syndrome. Lancet Neurol 2008;7:939-50.

Eldar AH, Chapman J. Guillain Barré syndrome and other immune mediated neuropathies: Diagnosis and classification. Autoimmun Rev 2014;13:525-30.

Yuki N, Hartung HP. Guillain-Barré syndrome. N Engl J Med 2012;366:2294-304.

Shahrizaila N, Yuki N. Bickerstaff brainstem encephalitis and Fisher syndrome: Anti-GQ1b antibody syndrome. J Neurol Neurosurg Psychiatry 2013;84:576-83.

Ito M, Kuwabara S, Odaka M, Misawa S, Koga M, Hirata K, et al. Bickerstaff’s brainstem encephalitis and Fisher syndrome form a continuous spectrum: Clinical analysis of 581 cases. J Neurol 2008;255:674-82.

Published

07-02-2023

How to Cite

KULSHRESTHA, M., and A. KULSHRESTHA. “BICKERSTAFF BRAINSTEM ENCEPHALITIS AND MILLER FISHER SYNDROME – VARIANT OF GUILLAIN-BARRÉ SYNDROME A SPECTRUM OF CLINICAL MANIFESTATION OF SAME DISEASE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 2, Feb. 2023, pp. 4-5, doi:10.22159/ajpcr.2023.v16i2.47372.

Issue

Section

Case Study(s)