HYPOGLYCEMIC ACTION OF ETHANOLIC EXTRACT OF LEAVES OF OXALIS CORNICULATA LINN. ON NORMAL AND ALLOXAN-INDUCED DIABETIC ALBINO RATS

Shobhit Kaushik; Jayant Rai; Madhulika Peter Samuel; Shipra Kaushik

doi:10.22159/ajpcr.2023.v16i7.47536

Authors

Shobhit Kaushik Department of Anaesthesiology, GS Medical College and Hospital, Hapur, Uttar Pradesh, India.
Jayant Rai Department of Pharmacology, GS Medical College and Hospital, Hapur, Uttar Pradesh, India.
Madhulika Peter Samuel Department of Pharmacology, S J P Medical College, Bharatpur, Rajasthan, India.
Shipra Kaushik Department of Pharmacology, GS Medical College and Hospital, Hapur, Uttar Pradesh, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i7.47536

Keywords:

Hypoglycemic activity, Alloxan, Oxalis corniculata

Abstract

Objective: The aim of the study is to evaluate hypoglycemic action of Ethanolic extract of leaves of Oxalis corniculata linn. on normal and Alloxan-induced diabetic albino rats.

Methods: Hyperglycemia is induced by use of intraperitoneal injection of Alloxan and Adrenaline. After that test drug Ethanolic extract of leaves of Oxalis corniculata (ELOC) and standard drug Glibenclamide in administered. The hypoglycemic effect of ELOC is compared with the standard drug and control.

Results: Significant hypoglycemic activity of ELOC was seen in Alloxan induced hyperglycemia when blood glucose levels were estimated from different tissues. Also, significant hypoglycemic activity of ELOC was seen in Adrenaline induced hyperglycemia.

Conclusion: Ethanolic extract of leaves of Oxalis corniculata (ELOC) possess hypoglycemic activity.

Key words: hypoglycemic activity, Alloxan, Oxalis corniculata

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