A CROSS-SECTIONAL STUDY TO EVALUATE ACUTE KIDNEY INJURY IN SCRUB TYPHUS PATIENTS
DOI:
https://doi.org/10.22159/ajpcr.2023.v16i4.47550Keywords:
Acute kidney injury, Scrub typhus, RIFLE criteriaAbstract
Objective: This study was conducted with the objective to estimate the incidence and severity of acute kidney injury (AKI) scrub typhus patients.
Methods: This was a cross-sectional study conducted 90 patients diagnosed with scrub typhus in a tertiary care center. Basic demographic and treatment details of the patients were recorded. Routine hematological investigations and biochemical profiles were performed upon admission and follow-up. AKI was defined and classified based on the RIFLE criteria.
Results: Mean age of the patients was 49.0±19.5 years and female preponderance was observed. The hemoglobin level was significantly lower in AKI patients as compared to non-AKI patients. Meanwhile, there was a significant increase in mean TLC count, CRP, total bilirubin in AKI patients as compared to non-AKI patients. was significantly higher as compared to those without AKI. Increasing age, ICU admission, shock, urinary abnormalities, and mechanical ventilation were the factors significantly associated with AKI.
Conclusion: AKI is a frequently reported complication in scrub typhus patients. In evaluating febrile illness associated with AKI, scrub typhus should be considered.
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