HISTOPATHOLOGICAL SPECTRUM OF THYROID LESIONS AT TERTIARY CARE HOSPITAL IN WESTERN RAJASTHAN

Authors

  • Divya Goyal Department of Pathology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.
  • S R Negi Department of Pathology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.
  • Abdul Sajid Department of Pathology, S. P. Medical College, Bikaner, Rajasthan, India.
  • Paridhi Ahuja Department of Otorhino-laryngology, S. M. S. Medical College, Jaipur, Rajasthan, India.

DOI:

https://doi.org/10.22159/ajpcr.2023.v16i10.47848

Keywords:

Thyroid neoplasm, Histomorphological, Criteria

Abstract

Objective: The objective of the study is to determine the proportion of different patterns (colloid goiter, colloid cyst, papillary carcinoma, etc.) of thyroid lesions among the patients who have undergone surgical treatment.

Methods: This was prospective and retrospective study to be conducted on 100 thyroidectomy specimens received in 5-year period (2016–2020) in Department of Pathology in Dr. S.N. Medical College, Jodhpur.

Results: Age ranged from 10 days to 85-year-old, Peak incidence of thyroid diseases was seen in the third to fifth decade, 78% non-neoplastic lesion, Adenomatous goiter was the most common non-neoplastic lesion (65%), Papillary carcinoma was the most common malignant lesion encountered.

Conclusion: Although non-invasive techniques like aspiration cytology provide a diagnosis in most, the ultimate answer often rests with histopathological examination of thyroidectomies, which forms the mainstay for a definitive diagnosis. Thorough gross and microscopic evaluation of thyroidectomies is mandatory even for non-neoplastic lesions as they sometimes harbor neoplasms.

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Author Biographies

Divya Goyal, Department of Pathology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.

Resident, Department of Pathology

S R Negi, Department of Pathology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.

Senior professor, Department of Pathology

Abdul Sajid, Department of Pathology, S. P. Medical College, Bikaner, Rajasthan, India.

Resident, Department of Pathology

Paridhi Ahuja, Department of Otorhino-laryngology, S. M. S. Medical College, Jaipur, Rajasthan, India.

Senior resident, Department of Otorhino-laryngology

References

Shenoy R. Manipal Manual of Surgery with Clinical Methods. 2nd ed. Vol. 20. New Delhi: CBS Publishers and Distributors Pvt. Limited; 2010. p. 311.

Sreedevi A, Sheela K. Histopathological spectrum of non-neoplastic and neoplastic lesions of thyroid-2 year study in a tertiary care teaching hospital. J Med Sci Clin Res 2018;6:514-9.

Unnikrishnan AG, Menon UV. Thyroid disorders in India: An epidemiological perspective. Indian J Endocrinol Metab 2011;15;Suppl 2:S78-81. doi: 10.4103/2230-8210.83329, PMID 21966658

Bamanikar S, Bamanikar A, Jadhav S, Jadhav P, Kumar H, Soraisham P. Cyto-histology and clinical correlation of thyroid gland lesions: A 3 year study in a tertiary hospital. Clin Cancer Investig J 2014;3:208-12. doi: 10.4103/2278-0513.132112

Bhargava S, Bansal R, Elhence P, Pandey S, Makkar N. Cyto-histological correlation of thyroid lessions with estrogen and progesterone receptor status on neoplastic leisons. J Clin Diagn Res 2012;6:811-5.

Padmavathi M, Raj JA. Histopathological spectrum of non-neoplastic and neoplastic lesions of thyroid: A 5-year prospective study in a tertiary care hospital. Int J Med Sc 2017;3:63-8.

Tsegaye B, Ergete W. Histopathologic pattern of thyroid disease. East Afr Med J 2003;80:525-8. doi: 10.4314/eamj.v80i10.8755, PMID 15250625

Ijomone EA, Duduyemi BM, Udoye E, Nwosu SO. Histopathological review of thyroid diseases in southern Nigeria-a ten year retrospective study. J Med Med Sci 2014;5:127-32.

Prabha V, Bhuvaneswari MG. A study of histopathological spectrum of thyroid lesions: An observational study. Int J Sci Stud 2019;7:1-4.

Koyuncuer A, Bayraktar SG, ErenGürkan EG. Histopathologic examination of thyroidectomy specimens from 1149 nodular goiter patient. Acta Med Mediterr 2016;32:35-43.

Bukhari U, Sadiq S. Histopathological audit of goiter: A study of 998 thyroid lesions. Pak J Med Sci 2008;24:442-6.

Qureshi IA, Khabaz MN, Baig M, Begum B, Abdelrehaman AS, Hussain MB. Histopathological findings in goiter: A review of 624 thyroidectomies. Neuro Endocrinol Lett 2015;36:48-52. PMID 25789588

Albasri A, Sawaf Z, Hussainy AS, Alhujaily A. Histopathological patterns of thyroid disease in al-Madinah region of Saudi Arabia. Asian Pac J Cancer Prev. 2014;15:5565-70. doi: 10.7314/ apjcp.2014.15.14.5565, PMID 25081665

Garcia E, Osterbauer B, Parham D, Koempel J. The incidence of microscopic thyroglossal duct tissue superior to the hyoid bone. Laryngoscope 2019;129:1215-7. doi: 10.1002/lary.27291. PMID 30194760

Ahmed Z, Chaudhary R, Umaru N. Study of prevalence of thyroid lesions in coastal region of Karnataka. J Evol Med Dent Sci 2013;2:6995-7002. doi: 10.14260/jemds/1245

Baloch ZW, LiVolsi VA. Our approach to follicular-patterned lesions of the thyroid. J Clin Pathol 2007;60:244-50. doi: 10.1136/ jcp.2006.038604, PMID 16798933

Published

07-10-2023

How to Cite

Goyal, D., S. R. Negi, A. Sajid, and P. Ahuja. “HISTOPATHOLOGICAL SPECTRUM OF THYROID LESIONS AT TERTIARY CARE HOSPITAL IN WESTERN RAJASTHAN”. Asian Journal of Pharmaceutical and Clinical Research, vol. 16, no. 10, Oct. 2023, pp. 186-90, doi:10.22159/ajpcr.2023.v16i10.47848.

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