ACTIVITY OF INDIAN TOPICAL SKIN PHARMACEUTICALS AGAINST SOME FUNGAL PATHOGENS
Abstract
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Objective: The aim was to assess the in vitro antifungal activity of some locally available pharmaceutical preparations used to cure skin diseases. Most
commonly used preparations were evaluated for dermatophytic and non-dermatophytic fungi viz., Aspergillus niger, Trichophyton rubrum, Candida
albicans, rhizopus microspores and Cryptococcus neoformis.
Methods: Disc diffusion method was used for inhibition zone of different preparations.
Results: When compared with different preparations used against skin diseases, Zalim lotion were found to be highly active against T. rubrum,
C. albicans, Rhizosporus microsporus.
Conclusion: The result obtained from the experiment suggests broad spectrum activity of Zalim lotion against dermatophytic and non-dermatophytic fungi.
Keywords: Antifungal, Tinea, Dermatophytic, Rubrum, Aspergillus.
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References
Kauffman CA. Fungal infections. Proc Am Thorac Soc 2006;3:35-40.
Rapp RP. Changing strategies for the management of invasive fungal infections. Pharmacotherapy 2004;24(2 pt 2):4S-28;29.
Cavaleiro C, Pinto E, Gonçalves MJ, Salgueiro L. Antifungal activity of Juniperus essential oils against dermatophyte, Aspergillus and Candida strains. J Appl Microbiol 2006;100:1333-8.
Pina-Vaz C, Gonçalves Rodrigues A, Pinto E, Costa-de-Oliveira S, Tavares C, Salgueiro L, et al. Antifungal activity of thymus oils and their major compounds. J Eur Acad Dermatol Venereol 2004;18(1):73‑8.
Pinto E, Pina-Vaz C, Salgueiro L, Gonçalves MJ, Costa-de-Oliveira S, Cavaleiro C, et al. Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species. J Med Microbiol 2006;55(Pt 10):1367-73.
Gupta AK, Cooper EA. Update in antifungal therapy of dermatophytosis. Mycopathologia 2008;166(5-6):353-67.
Dahdah MJ, Sher RK. Dermatophytes. Curr Fungal Infect Rep 2008;2:81-6.
Andrews MD, Burns M. Common tinea infections in children. Am Fam Physician 2008;77:1415-20.
Gupta AK, Chow M, Daniel CR, Aly R. Treatments of tinea pedis. Dermatol Clin 2003;21(3):431-62.
Andriole VT. The 1998 Garrod lecture. Current and future antifungal therapy: New targets for antifungal agents. J Antimicrob Chemother 1999;44(2):151-62.
Esteban A, Abarca ML, Cabañes FJ. Comparison of disk diffusion method and broth microdilution method for antifungal susceptibility testing of dermatophytes. Med Mycol 2005;43(1):61-6.
Rao S, Abdul R, Bhargavi C, Prathusha R. Comparative in vitro study of different antifungal agents on selective pathogenic fungi. Adv Bio Tech 2013;13(1):131-81.
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