A STUDY ON CLINICOETIOLOGY AND OUTCOME IN A PATIENT WITH ACUTE PANCREATITIS
DOI:
https://doi.org/10.22159/ajpcr.2023.v16i7.48760Keywords:
Severe Acute PancreatitisAbstract
Objectives: Acute pancreatitis (AP) is a common problem in medical practice. Mild AP recovers spontaneously within 1 week. Whereas high-grade AP patients suffer with severe complications such as necrosis and finally landing organ failure. The prognosis in these cases is very poor. This study was conducted to examine the clinical features, causative factors, and consequences of AP.
Methods: This study was conducted in the Department of general surgery, S.V.R.R.G.G.H, Sri Venkateswara Medical College, Tirupati, after taking Institutional Ethical Committee from March 2021 to March 2023. 100 cases are taken for study.
Results: Age group of patients included in this study was 18–70 years. The mean age of presentation is noted in this study was 38–86 years. Alcohol consumption is the most common causative factor identified in this study which is about 62%. Most of the cases presented with pain abdomen (90%) followed by vomiting (77%). Other clinical manifestations are abdominal distention (24%) and Jaundice (10%).
Conclusion: Alcohol is the most common etiology being identified of about 62% of cases followed by gallstones 30%. The most common presenting complaints were abdominal pain and vomiting. The combination of serum amylase and serum lipase provided high sensitivity (95%) for the diagnosis of AP. Computed tomography was a non-invasive method of diagnosing and imaging complications.
Downloads
References
Dobosz M, Mionskowska L, Hac S, Dobrowolski S, Dymecki D, Wajda Z. Heparin improves organ microcirculatory disturbances in caerulein-induced acute pancreatitis in rats. World J Gastroenterol 2004;10:2553-6. doi: 10.3748/wjg.v10.i17.2553, PMID 15300904
Kylänpää ML, Repo H, Puolakkainen PA. Inflammation and immunosuppression in severe acute pancreatitis. World J Gastroenterol 2010;16:2867-72. doi: 10.3748/wjg.v16.i23.2867, PMID 20556831
Gross V, Leser HG, Heinisch A, Schölmerich J. Inflammatory mediators and cytokines--new aspects of the pathophysiology and assessment of severity of acute pancreatitis? Hepatogastroenterology 1993;40:522-30. PMID 7509768
Balthazar EJ. Acute pancreatitis: Assessment of severity with clinical and CT evaluation. Radiology 2002;223:603-13. doi: 10.1148/radiol.2233010680, PMID 12034923
Toh SK, Phillips S, Johnson CD. A prospective audit against national standards of the presentation and management of acute pancreatitis in the South of England. Gut 2000;46:239-43. doi: 10.1136/gut.46.2.239, PMID 10644319
Pupelis G, Zeiza K, Plaudis H, Suhova A. Conservative approach in the management of severe acute pancreatitis: Eight- year experience in a single institution. HPB (Oxford) 2008;10:347-55. doi: 10.1080/13651820802140737, PMID 18982151
Büchler MW, Gloor B, Müller CA, Friess H, Seiler CA, Uhl W. Acute necrotizing pancreatitis: Treatment strategy according to the status of infection. Ann Surg 2000;232:619-26. doi: 10.1097/00000658- 200011000-00001, PMID 11066131
Sand J, Välikoski A, Nordback I. Alcohol consumption in the country and hospitalizations for acute alcohol pancreatitis and liver cirrhosis during a 20- year period. Alcohol Alcohol 2009;44:321-5. doi: 10.1093/
alcalc/agn121, PMID 19144980
Sekimoto M, Koizumi M, Takada T, Kawarada Y, Hirata K, Mayumi T, et al. JPN guidelines for the management of acute pancreatitis: Epidemiology, etiology, natural history, and outcome predictors in acute pancreatitis. J Hepatobiliary Pancreat Surg 2006;13:10-24.
Ammori BJ, Boreham B, Lewis P, Roberts SA. The biochemical detection of biliary etiology of acute pancreatitis on admission: Arevisit in the modern era of biliary imaging. Pancreas 2003;26:e32-5. doi: 10.1097/00006676-200303000-00023, PMID 12604925
Mortele KJ, Wiesner W, Intriere L, Shankar S, Zou KH, Kalantari BN, et al. A modified CT severity index for evaluating acute pancreatitis: Improved correlation with patient outcome. AJR Am J Roentgenol 2004;183:1261-5. doi: 10.2214/ajr.183.5.1831261, PMID 15505289
Published
How to Cite
Issue
Section
Copyright (c) 2023 VALLURU SIVARAMAKRISHNA, PURUSHOTHAMG, YAMALA ANAND BABU, PADALA ADITYA
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.
