A STUDY OF DRUG UTILIZATION PATTERN OF ANALGESICS IN POST-OPERATIVE PATIENTS IN A TERTIARY CARE HOSPITAL
DOI:
https://doi.org/10.22159/ajpcr.2024.v17i2.48775Keywords:
Drug utilization study, Post-operative pain, Analgesic, Monotherapy, DiclofenacAbstract
Objectives: The objective of the study was to evaluate the utilization pattern of analgesic use in post-operative wards of different surgical specialties.
Methods: The study was observational and retrospective conducted, for 4 months from November 2022 to February 2023 in Tezpur Medical College, Assam and data were collected from 80 patients’ case sheets regarding analgesics prescribed during post-operative days, their route of administration, mono/combined therapy.
Results: Non-steroidal anti-inflammatory medications (NSAIDs) as diclofenac (55.5%) and paracetamol (32.5%) were commonly prescribed for relief, both in monotherapy and combination therapy. Tramadol, an opioid was also used for severe pain relief and then shifted to NSAIDs. All patients were prescribed injectable analgesics on the day of surgery and the 1st post-operative day. Combination of aceclofenac + paracetamol (7.70%) was the most prescribed oral analgesic followed by tramadol + paracetamol (3.50%), mostly prescribed as brand names.
Conclusion: Diclofenac was the most used NSAID in post-operative pain both in mono and combined therapy and the prescribing pattern was not rational related to more use of brand names.
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References
WHO Expert Committee. Introduction to Drug Utilization Research. Geneva: World Health Organization; 2003. Available from: https://iris. who.int/bitstream/handle/10665/42627/924156234X.pdf [Last accessed on 2013 Jul 25].
Chandrakantha T, Rajesh B, Neha K. Drug utilization pattern of analgesics among post-operative patients in a tertiary care hospital: A prospective study. Indian J Pharm Pharmacol 2019;6:137-41.
Barawade S, Gursale S. A study of drug utilization pattern of analgesics in postoperative patients of tertiary care hospital. MedPulse Int J Pharmacol 2017;1:28-32.
Chaudhary A, Sarraf DP, Gupta AK, Khadka DB, Jayswal A, Dhakal A, et al. Prescribing pattern of analgesics in hospitalized patients in surgical unit at Nepalgunj medical college and teaching hospital. J Karnali Acad Health Sci 2022;5:2-4.
Parulekar VV, Badar VA. Observing drug utilization trends of analgesics in indoor surgical patients in tertiary care teaching hospital. Asian J Pharm Clin Res 2020;13:47-50. doi: 10.22159/ajpcr.2020.v13i5.37062
Dasta JF, Fuhrman TM, McCandles CR. Patterns of prescribing and administering drugs for agitation and pain in patients in a surgical intensive care unit. Crit Care Med 1994;22:974-80. doi: 10.1097/00003246-199406000-00016, PMID 8205830
Dashputra AV, Badwaik RT. Utilization of analgesics in perioperative cases of teaching hospital. Int J Med Pharm Sci 2013;3:14-9.
Ehikhamenor EE, Aghahowa SE, Azodo CC. Retrospective evaluation of analgesics prescribing pattern in A Tertiary Hospital in Nigeria. J Med Biomed Res 2002;11:71-7.
Chaudhari JS, Kubavat AR, Mistry VR, Pandya AS, Hotchandani SC, Patel BS. A drug utilization study of analgesics for management of postoperative pain in patients admitted at a tertiary care teaching hospital. Int J Basic Clin Pharmacol 2013;2:757-62. doi: 10.5455/2319- 2003.ijbcp20131216
Vallano A, Aguilera C, Arnau JM, Baños JE, Laporte JR. Management of postoperative pain in abdominal surgery in Spain. A multicentre drug utilization study. Br J Clin Pharmacol 1999;47:667-73. doi: 10.1046/j.1365-2125.1999.00962.x, PMID 10383545
Kumarasingam T, Revathy S, Mukherjee D. Drug utilization pattern of analgesics among postoperative patients in a tertiary care hospital. Pharm Lett 2014;6:40-6.
National List of Essential Medicines, India; 2011. Available from: https://apps.who.int/medicinedocs/documents/s18693en/s18693en.pdf [Last accessed on 2017 May 05].
Bhansali NB, Gosai TR, Dholaria NK, Suthar SD, Chacko J, Chavda DA, et al. Drug utilization study in post-operative patients in surgical ward of a tertiary hospital attached with medical college. Pharm Lett 2013;5:251-7.
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Copyright (c) 2023 Dr Daradi Das, Dr Dhrubajyoti Borah, Dr Pinaki Chakravarty, Dr Ali Nahdi Yashin
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