MAGNETIC RESONANCE IMAGING IN DIAGNOSIS AND CLASSIFICATION OF MULLERIAN DUCT ANOMALIES: CASE SERIES

Authors

  • BHAVYA KATARIA Department of Radiodiagnosis, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
  • SHIBANI MEHRA Department of Radiodiagnosis, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India

DOI:

https://doi.org/10.22159/ajpcr.2024v17i11.52702

Keywords:

Magnetic resonance imaging, Mullerian duct anomalies, Ultrasonography

Abstract

Objectives: Mullerian duct anomalies (MDAs) arise from the aberrant development of the uterus, cervix, and vagina, impacting the potential for successful conception and full-term pregnancy. This category encompasses a diverse range of developmental defects, leading to a spectrum of clinical presentations such as amenorrhea, infertility, recurrent miscarriages, intrauterine growth retardation, malposition of the fetus, preterm labor, and retained placenta.

Case(s): In this study, we present 17 cases of MDA with a wide array of clinical manifestations. The varied symptoms included amenorrhea, infertility, repeated miscarriages, intrauterine growth retardation, malposition of the fetus, preterm labor, and retained placenta. Accurate categorization of these cases is crucial for determining the appropriate surgical intervention. While ultrasonography aids in the initial diagnosis of MDA, our focus on accurate classification necessitates the use of magnetic resonance imaging (MRI).

Conclusion: Our findings underscore the significance of MRI in precisely categorizing MDA, and facilitating effective management strategies. The 17 cases presented demonstrate the diverse spectrum of MDA manifestations, emphasizing the need for tailored surgical interventions for successful conception and optimal pregnancy outcomes. The use of MRI proves instrumental in guiding clinical decisions, offering a comprehensive understanding of MDA, and informing targeted interventions to enhance reproductive success.

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References

Chandler TM, Machan LS, Cooperberg PL, Harris AC, Chang SD. Mullerian duct anomalies: from diagnosis to intervention. Br J Radiol. 2009 Dec;82(984):1034-42. doi: 10.1259/bjr/99354802, PMID 19433480.

Grover SB, Antil N, Katyan A, Rajani H, Grover H, Mittal P, et al. Niche role of MRI in the evaluation of female infertility. Indian J Radiol Imaging. 2020 Jan-Mar;30(1):32-45. doi: 10.4103/ijri.IJRI_377_19, PMID 32476748.

Sugi MD, Penna R, Jha P, Pōder L, Behr SC, Courtier J, et al. Müllerian duct anomalies: role in fertility and pregnancy. RadioGraphics. 2021 Oct;41(6):1857-75. doi: 10.1148/rg.2021210022, PMID 34597219.

Garratt J, Siegelman ES. MR imaging of Müllerian anomalies. Magn Reson Imaging Clin N Am. 2023;31(1):11-28. doi: 10.1016/j. mric.2022.06.002, PMID 36368856.

Marten K, Vosshenrich R, Funke M, Obenauer S, Baum F, Grabbe E. MRI in the evaluation of Müllerian duct anomalies. Clin Imaging. 2003 Sep-Oct;27(5):346-50. doi: 10.1016/s0899-7071(02)00587-9, PMID 12932688.

Behr SC, Courtier JL, Qayyum A. Imaging of Müllerian duct anomalies. RadioGraphics. 2012 Oct;32(6):E233-50. doi: 10.1148/rg.326125515, PMID 23065173.

El Ameen NF, Ebraheem MA, Nour El Dien NM. MR assessment of Müllerian duct anomalies: does it help? Egypt J Radiol Nucl Med. 2014;45(2):561-7. doi: 10.1016/j.ejrnm.2014.02.006.

Olpin JD, Moeni A, Willmore RJ, Heilbrun ME. MR imaging of Müllerian fusion anomalies. Magn Reson Imaging Clin N Am. 2017 Aug;25(3):563-75. doi: 10.1016/j.mric.2017.03.008, PMID 28668160.

Jegannathan D, Indiran V. Magnetic resonance imaging of classified and unclassified Müllerian duct anomalies: comparison of the American Society for Reproductive Medicine and the European Society of Human Reproduction and Embryology classifications. SA J Radiol. 2018 Apr 23;22(1):1259. doi: 10.4102/sajr.v22i1.1259, PMID 31754489.

Robbins JB, Broadwell C, Chow LC, Parry JP, Sadowski EA. Müllerian duct anomalies: embryological development, classification, and MRI assessment. J Magn Reson Imaging. 2015 Jan;41(1):1-12. doi: 10.1002/ jmri.24771, PMID 25288098.

Guo X, Sun X, Xu H, Si S, Yu B, Liu J. Successful pregnancy in each half uterus cavity of the septate uterus after transferring three embryos in one half-cavity: a case report. J Ovarian Res. 2013;6(1):56. doi: 10.1186/1757-2215-6-56, PMID 23924779.

Selvaraj P, Selvaraj K. Reproductive outcome of septate uterus following hysteroscopic septum resection. J Hum Reprod Sci. 2010 Sep;3(3):143-5. doi: 10.4103/0974-1208.74157, PMID 21234176.

Carrera M, Pérez Millan F, Alcázar JL, Alonso L, Caballero M, Carugno J, et al. Effect of hysteroscopic metroplasty on reproductive outcomes in women with septate uterus: systematic review and meta-analysis. J Minim Invasive Gynecol. 2022 Apr;29(4):465-75. doi: 10.1016/j. jmig.2021.10.001, PMID 34648934.

Published

07-11-2024

How to Cite

BHAVYA KATARIA, and SHIBANI MEHRA. “MAGNETIC RESONANCE IMAGING IN DIAGNOSIS AND CLASSIFICATION OF MULLERIAN DUCT ANOMALIES: CASE SERIES”. Asian Journal of Pharmaceutical and Clinical Research, vol. 17, no. 11, Nov. 2024, pp. 1-6, doi:10.22159/ajpcr.2024v17i11.52702.

Issue

Section

Case Study(s)