CYSTS OF THE CENTRAL NERVOUS SYSTEM: A REVIEW OF 35 CASES WITH OUTCOMES
DOI:
https://doi.org/10.22159/ajpcr.2024v17i11.52822Keywords:
Cyst, Clinical features, HistopathologyAbstract
Objective: Non-neoplastic, non-inflammatory cysts of the central nervous system (CNS) may cause symptoms as a result of changes in pressure, rupture or secondary inflammation. The cyst-related details, such as its age, site, cyst wall, and its contents, also provide an insight into their embryology and histogenesis. This paper reviews the clinic-pathological features of cysts of CNS.
Methods: In this study, a prospective analysis of the cysts of CNS diagnosed between November 2019 and October 2023 who presented to our outpatient department and managed at Command Hospital Lucknow and Base Hospital Delhi Cantt were reviewed. Written informed consent was taken from all patients. Cystic degeneration in tumors or inflammatory lesions was excluded from the study.
Results: There were 35 cysts in the study period of 04 years. Majority of intracranial cysts presented with signs of raised intracranial pressure. Patients with epidermoid cysts had additional cerebellar signs, visual disturbances and deafness. Cord compression is the main presentation of all spinal cysts.
Conclusion: Cysts of CNS are usually maldevelopment in nature. A few are acquired. The radiological identification of these cysts and pathological confirmation is necessary for prognostic purposes.
Downloads
References
Russel DS, Rubinstein LJ. Pathology of Tumours of the Nervous System. 5th ed. Baltimore: Williams and Wilkins; 1989. p. 693-5.
Obana WG, Wilson CB. Epidermoid cysts of the brain stem. Report of three cases. J Neurosurg.1991;74:123-8.
Roux A, Mercier C, Larbrisseau A, Dube LJ, Dupuis C, Del Carpio R. Intramedullary epidermoid cysts of the spinal cord. Case report. J Neurosurg. 1992;76:528-33.
Toglia JU, Netsky MG, Alexander E Jr. Epithelial (epidermoid) tumours of the cranium. Their common nature and pathogenesis. J Neurosurg. 1965;23:384-93.
Yamakawa K, Shitara N, Genka S, Manaka S, Takakura K. Clinical course and surgical prognosis of 33 cases of intracranial epidermoid tumors. Neurosurgery. 1989;24:568-73.
Lihara K, Kikuchi M, Ishikawa M. Epidermoid cyst traversing the pons into the fourth ventricle. A case report. Surg Neurol. 1989;32:377-81.
Mc Lendon RE. Epidermoid and dermoid tumours: Pathology. Wilkins RM, Rengachary SS, editors. Neurosurgery. 2nd ed., Vol. 1. New York: McGraw-Hill; 1996. p. 959-64.
Guner M, Shaw MD, Turner JW, Steven JL. Computed tomography in the diagnosis of colloid cyst. Surg Neurol. 1976;6:345-8.
Maeder PP, Holtas SL, Turner JW, Salford LG, Tapper UA, Brun A, et al. Colloid cysts of the third ventricle: Correlation of MR and CT findings with histology and chemical analysis. AJNR Am J Neuroradiol. 1990;11:575-81.
Voelker JL, Cambell RL, Muller J. Clinical, radiographic, and pathological features of symptomatic Rathke’cleft cysts. J Neurosurg. 1991;74:535-44.
Leech RW, Olafson RA. Epithelial cysts of the neuraxis: Presentation of three cases and a review of the origins and classification. Arch Pathol Lab Med. 1977;101:196-202.
Rengachary SS, Kennedy JD. In: Wilkins RH, Rangachary SS, editors. Intracranial Archnoid and Ependymal Cysts. 2nd ed., Vol. 3. New York: McGraw-Hill; 1996. p. 3709-28.
Published
How to Cite
Issue
Section
Copyright (c) 2024 ASHOK KUMAR
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.