VARIED CLINICAL PRESENTATIONS OF CHANCROID: A CASE SERIES AND LITERATURE REVIEW

Authors

  • SPANDAN K. SHAH Department of Dermatology, Parul Institute of Medical Sciences and Research, tal. Limda, Waghodia, Vadodara https://orcid.org/0009-0007-9595-5537
  • KRUNAL TRALSAWALA Department of Dermatology, Parul Institute of Medical Sciences and Research, tal. Limda, Waghodia, Vadodara
  • DHARA D. PATEL Department of Dermatology, Parul Institute of Medical Sciences and Research, tal. Limda, Waghodia, Vadodara
  • SOM J LAKHANI Department of Dermatology, Parul Institute of Medical Sciences and Research, tal. Limda, Waghodia, Vadodara

DOI:

https://doi.org/10.22159/ajpcr.2024v17i12.52852

Keywords:

Chancroid, Sexually transmitted infections, Coinfections, Ulcer characteristics, Atypical presentations

Abstract

Objectives: This study aimed to explore the diverse clinical manifestations of chancroid, investigate associated coinfections, and evaluate treatment outcomes.

Methods: A prospective case series was conducted involving six patients diagnosed with chancroid. Each patient underwent a detailed clinical evaluation, with photographic documentation of lesions. Laboratory investigations were performed to confirm chancroid and identify potential coinfections. Treatment was tailored according to the clinical findings and diagnostic results.

Results: The study revealed a spectrum of atypical ulcer presentations, including phagedenic ulcers, large ulcers, and small discrete lesions, suggesting the influence of coexisting STIs. Laboratory evaluations confirmed the presence of coinfections such as HIV, syphilis, and herpes in several cases.

Conclusion: Chancroid can present with diverse and atypical clinical features, often in the context of coexisting STIs. Early diagnosis and appropriate management are critical to preventing complications and improving patient outcomes.

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References

Irizarry L, Velasquez J, Wray AA. Chancroid. Treasure Island, FL: StatPearls; 2020.

Best BM. Practice. Chancroid - Symptoms, diagnosis, and treatment 2023. Available from: https://bestpractice.bmj.com/topics/en-gb/932

World Health Organization. Eradicating Chancroid. Geneva: World Health Organization; 2008.

Loh AJ, Ting EL, Wi TE, Mayaud P, Chow EP, Santesso N, et al. The diagnostic accuracy of syndromic management for Genital Ulcer disease: A systematic review and meta-analysis. Front Med (Lausanne). 2021;8:806605. doi: 10.3389/fmed.2021.806605, PMID 35071282

World Health Organization. Eradicating Chancroid. Public Health Reviews. Geneva: World Health Organization; 2001;79(9):818-826.

Published

07-12-2024

How to Cite

SPANDAN K. SHAH, KRUNAL TRALSAWALA, DHARA D. PATEL, and SOM J LAKHANI. “VARIED CLINICAL PRESENTATIONS OF CHANCROID: A CASE SERIES AND LITERATURE REVIEW”. Asian Journal of Pharmaceutical and Clinical Research, vol. 17, no. 12, Dec. 2024, pp. 4-9, doi:10.22159/ajpcr.2024v17i12.52852.

Issue

Section

Case Study(s)