DIETARY INTERVENTION AND PROTEIN SUPPLEMENTATION IN CHRONIC KIDNEY DISEASE PATIENTS UNDERGOING HEMODIALYSIS
Abstract
ABSTRACT
Objective: The present study was conducted with the aim to assess and analyze the nutritional status of patients (>30yrs) undergoing haemodialysis.
Method: 50 subjects were enrolled in the study (32 males and 18 females). Various biochemical parameters such as Sodium, Potassium, Creatinine,
Phosphorus, Albumin etc along with amount of calorie and protein intake were compared pre and post nutritional counseling and protein
supplementation for 30 days during ongoing haemodialysis.
Result: Short term implication showed a significant statistical difference in the biochemical parameters. Adequate dietary counseling along with oral
nutritional supplementation given during haemodialysis improved the nutritional status of malnourished Chronic Kidney Disease patient. About 81%
of the patients showed proficient response whereas the remaining 18% showed a moderate improvement in their nutritional status.
Conclusion: Patients undergoing haemodialysis commonly develop protein-energy malnutrition which is associated with poor survival. Special
nutritional care is required for the dialysis patient to improve the net protein anabolism.
Keywords: Hemodialysis, Protein, Chronic kidney disease, Nutritional status, Malnutrition.
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References
REFERENCES
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Fig. 1: The increase in the calorie intake and comparison to the ideal requirement
Fig. 2: The increase in the protein intake and comparison to the ideal requirement
Table 2: Depicting the macronutrient requirements for the HD patients[16]
Macronutrients and fiber
DPI
2 g/kg/day (at least 50% of high biological value)
DEI
Kcal/kg/day
Total fat
-30% of total energy intake
Carbohydrates
-55% of total energy intake (especially complex carbohydrates)
Total fiber
-25 g/day
DPI: Dietary protein intake, DEI: Daily energy intake, HD: Hemodialysis
Table 3: Depicting the micronutrient requirement by the HD patients[16]
Minerals and water (range of intake)
Sodium
-2000 mg/day
Potassium
-2750 mg/day
Phosphorus
-1000 mg/day
Calcium
<1000 mg/day
Magnesium
-300 mg/day
Iron
-18 mg/day
Water
Usually 750-1500 ml/day
HD: Hemodialysis
Table 4: Depicting the changes in the anthropometric and biochemical parameters of the subjects
Parameters
Male
Female
Pre
Post
Pre
Post
Body weight (kg)
±4.5
5±4.5
6±3
1±3
BMI (kg/m2)
5±1.5
9±1.5
3±1.5
9±1.5
Sodium
6±0.5
3±0.5
2±0.5
5±0.5
Potassium
8±0.5
5±0.5
1±0.5
9±0.5
Phosphorus
6±0.5
5±0.5
3±0.5
4±0.5
Serum albumin (g/L)
89±0.2
44±0.2
94±0.2
36±0.2
Creatinine (mg/dl)
4±1.5
5±1.5
1±1.2
6±1.2
Cholesterol (mg/dl)
8±45
±45
±45
±45
Triglycerides (mg/dl)
1±50
±50
4±50
6±50
BMI: Body mass index
Asian J Pharm Clin Res, Vol 8, Issue 4, 2015, 230-232
Cheenam and Leena
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