DRUG INTERACTION INDUCED PHENYTOIN TOXICITY: A CASE REPORT
Abstract
Phenytoin is a narrow therapeutic indexed antiepileptic drug. Many drugs competitively inhibit isoenzymes responsible for its metabolism when concurrently administered and increases the phenytoin plasma concentration leading to serious adverse effects. One such case is being reported with phenytoin toxicity due to concurrent administration of phenytoin and Isoniazid.
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