APPLICATION OF GREEN EXTRACTION METHODS TO RESVERATROL EXTRACTION FROM PEANUT (ARACHIS HYPOGAEA L.) SKIN

Authors

  • REZI RIADI SYAHDI Department of Pharmacognosy Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
  • RATNA NADYANA Department of Pharmacognosy Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
  • RIZQI HERU PUTRI Department of Pharmacognosy Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
  • ROSEDIANA SANTI epartment of Biomedical Computation, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
  • ABDUL MUN’IM Department of Pharmacognosy Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia

DOI:

https://doi.org/10.22159/ijap.2020.v12s1.FF003

Keywords:

Arachis hypogaea, Extraction, Ionic liquid, Natural deep eutectic solvent, Resveratrol

Abstract

Objective: This study compared the maceration extraction method with non-conventional extraction methods such as ultrasound-assisted extraction
(UAE) and microwave-assisted extraction (MAE).
Methods: To obtain resveratrol, various conditions were optimized: Solvent types (organic solvent [i.e. 70% ethanol] and green solvents [i.e. natural
deep eutectic solvent (NADES) and ionic liquid (IL)]) and extraction methods. The resveratrol content in the extracts was analyzed by high-performance
liquid chromatography.
Results: It was determined that resveratrol extracted by UAE with NADES was composed of choline chloride–oxalic acid when the following
conditions were used: The solid/liquid ratio of 1:20 (g/mL) and the extraction time of 15 min. These conditions produced higher resveratrol content
(0.049 mg/g dry weight) than that using MAE with 70% ethanol (0.011 mg/g dry weight). However, the maceration method yielded the highest
amount of resveratrol (0.221 mg/g dry weight), and MAE with IL produced the smallest amount of resveratrol (0.157 × 10−3 mg/g dry weight).
Conclusion: Peanut skin extracted using the maceration method produced the highest amount of resveratrol compared to that using other methods.

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Published

23-03-2020

How to Cite

SYAHDI, R. R., NADYANA, R., PUTRI, R. H., SANTI, R., & MUN’IM, A. (2020). APPLICATION OF GREEN EXTRACTION METHODS TO RESVERATROL EXTRACTION FROM PEANUT (ARACHIS HYPOGAEA L.) SKIN. International Journal of Applied Pharmaceutics, 12(1), 38–42. https://doi.org/10.22159/ijap.2020.v12s1.FF003

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