ANTI-CHOLOSETEROL ACTIVITIES OF WHITE (RAPHANUS RAPHANISTRUM) AND RED (RAPHANUS SATIVUS) RADISH ROOTS

NOVI YANTIH; WINDA DESTIANA; DIAH KARTIKA PRATAMI

doi:10.22159/ijap.2021.v13s2.05

Authors

NOVI YANTIH Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia
WINDA DESTIANA Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia
DIAH KARTIKA PRATAMI Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia

DOI:

https://doi.org/10.22159/ijap.2021.v13s2.05

Keywords:

Raphanus raphanistrum, Raphanus sativus, Cholesterol, Spectrophotometry

Abstract

Objective: The purpose of this research is to explore the in vitro activities of white (Raphanus raphanistrum) and red (Raphanus sativus) radish root ethanol extract in decreasing cholesterol levels.

Methods: Ultrasonification method was used in obtaining 96% ethanol extract of white and red radish root. The cholesterol levels were analyzed by visible spectrophotometry, which was validated using Lieberman-Buchard reagents. The decreased cholesterol levels were converted into IC₅₀ values.

Results: The results showed that the IC₅₀of 96% white and red radish root ethanol extracts were 743.7 and 634.7 µg/ml, respectively. The results of statistical analysis using the T-test obtained a significant value greater than the probability value (P) of 0.05.

Conclusion: Therefore, it was concluded that the activities of 96% ethanol extract of white and red radish roots did not have a significant ability to reduce the in vitro cholesterol levels.

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