DECOCTION OF POMEGRANATE (PUNICA GRANATUM L.) PEEL AS AN ANTHELMINTIC AGAINST TAENIA SAGINATA

NYI MEKAR SAPTARINI; RESMI MUSTARICHIE

doi:10.22159/ijap.2021.v13s4.43831

Authors

NYI MEKAR SAPTARINI Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, West Java, Indonesia 45363
RESMI MUSTARICHIE Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, West Java, Indonesia 45363

DOI:

https://doi.org/10.22159/ijap.2021.v13s4.43831

Keywords:

Albendazole, Motility assay, Dose-dependent, Isolated Taenia saginata

Abstract

Objective: The purpose of this study was to investigate the anthelmintic activity of pomegranate (Punica granatum L.) peel decoction against Taenia saginata.

Methods: The in vitro assay was conducted by observing the motility of T. saginata, which is isolated from cattle’s gastrointestinal tract, in various concentrations of pomegranate peel decoction with albendazole as a positive control.

Results: The results showed that the anthelmintic activity was dependent on decoction concentration and the duration of contact between decoction and nematode. Decoction at moderate concentration causes paralysis, while high concentration causes death. The 75% and 100% pomegranate peel decoction started to cause death at 240 min and 150 min after contact with T. saginata.

Conclusion: It was concluded that pomegranate peel decoction has anthelmintic activity.

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