PREPARATION AND CHARACTERIZATION OF FICUS LACOR METALLIC PARTICLES BASED NANOGEL FOR WOUND HEALING ACTIVITY
DOI:
https://doi.org/10.22159/ijcpr.2024v16i1.4016Keywords:
Wound healing, Nanotechnology, Silver nanoparticles, Green synthesis, Ficus lacorAbstract
Objective: Since there is no evidence of silver nanoparticle preparation using the Ficus lacor plant, our present study was designed to synthesise silver nanoparticles using a Ficus lacor leaves extract, which was expected to show an enhanced wound healing activity with greater advantages of green synthesis.
Methods: In the present study, silver nanoparticles were prepared using Ficus lacor leaf extract and the prepared nanoparticles were characterised by Ultraviolet-Visible spectroscopy and Particle size analysis later a topical gel is prepared and its effectiveness was evaluated by using animal excision wound model.
Results: The study results showed that the Ficus lacor-based silver nanoparticle topical gel on an animal excision wound model exhibited almost similar wound healing activity in comparison with standard marketed product.
Conclusion: This study concluded that Ficus lacor-silver nanoparticle gel showed considerable improvement in the excision wound model and hence this can be a promising candidate in wound healing.
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Copyright (c) 2024 CHAITHANYA K. J., MAHALAXMI C. PATIL, MOUMITA BANERJEE, ASHVINI H. M.
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