PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF ATLANTIA MONOPHYLLA (AM) EXTRACT

MANCHI HARITHA; BL KUDAGI; PATHAPATI RAMA MOHAN; VURIMI BHOPAL CHANDRA; SK SALMA KAMAL; RAJESH KUMAR MANCHI; ANJANI DEVI NELAVALA

doi:10.22159/ijcpr.2024v16i4.4078

Authors

MANCHI HARITHA Department of Pharmacology, Narayana Medical College, Nellore, Andhra Pradesh, India
BL KUDAGI Department of Pharmacology, Narayana Medical College, Nellore, Andhra Pradesh, India
PATHAPATI RAMA MOHAN Department of Pharmacology, Narayana Medical College, Nellore, Andhra Pradesh, India
VURIMI BHOPAL CHANDRA Department of Pharmacology, Narayana Medical College, Nellore, Andhra Pradesh, India
SK SALMA KAMAL Department of Pharmacology, Narayana Medical College, Nellore, Andhra Pradesh, India
RAJESH KUMAR MANCHI Department of Pharmacology, T. S. Misra Medical College, lucknow, India
ANJANI DEVI NELAVALA Department of Mental Health Nursing, Narayana College of Nursing, Nellore, Andhra Pradesh, India

DOI:

https://doi.org/10.22159/ijcpr.2024v16i4.4078

Keywords:

Atlantia monophylla, Aqueous extract, Antibacterial, Antifungal, Phytochemical analysis

Abstract

Objective: Plants have long been recognised for their wide range of biological properties, including antibacterial, analgesic, anticancer, antipyretic, and antihypertensive action. They are also a significant source of several chemicals with biological activity. The Rutaceae family consists of a small shrub Atlantia monophylla. It is available all over India. The leaves were employed as an insect repellent and to alleviate swellings. The root bark has been found to contain atalaphyllinine, atalantin, dehydroatalantin, cycloepiatalantin, and atalaphylline 3, 5-dimethyl ether. Essential oil extracted from the leaves was reported to have antimicrobial properties.

Methods: To evaluate the phytochemicals Standard chemical methods for each o the compounds were used – like Tannins (0.1% ferric chloride), saponins (2 ml of water)/flavonoids (with NaOH), Alkaloids (Drangandooff reagent), protein (Million’s reagent) steroids (10% sulphuric acid), anthraquinones (aqueous ammonia), Phenols (lead acetate), terpenoids, (3% sulphuric acids) Carbohydrates (Benedict’s reagent). Disc plate method was used to evaluate the antimicrobial activity of the extract

Results: The results of this study identified the presence of tannins, flavonoids, alkaloids, proteins, steroids, phenols, terpenoids, and carbohydrates in the AM extract. The microbiological studies revealed better inhibitions of microbes compared to standard drugs.

Conclusion: Tannins, flavonoids, proteins, steroids, phenols, terpenoids, carbohydrates and alkaloids were extracted from the AM extract. The extract has significant microbiological action.

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