EVALUATION OF THE POTENTIAL ROLE OF AQUEOUS LEAVES EXTRACT OF AVERRHOA CARAMBOLA FOR IN VITRO ANTICANCER STUDIES

Authors

  • SRILEGA I Department of Biochemistry, Annamalai University, Chidambaram, Tamil Nadu, India
  • KAVITHA M Department of Biochemistry, Annamalai University, Chidambaram, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ijls.2024.v12i1.49713

Keywords:

Ayurvedic, Skin disorders, Fungal skin infection, Phenols, Flavonoids, Antioxidants

Abstract

Objective: Averrhoa carambola is known as a tree. Averrhoa carambola leaves are commonly used in Ayurvedic and traditional Chinese medicine is used for inflammatory skin disorders and fungal skin infections. The leaves of star fruit are rich in Vitamin C and bioactive compounds such as phenols and flavonoids abundant sources of antioxidants.

Methods: The qualitative phytochemical study of these plant extracts indicates the presence of tannins, saponins, flavonoids, alkaloids, proteins, and phenol. The herb has been used traditionally from antiquity, in the treatment of neurological health, memory issues, and breast cancer. It chiefly possesses the pharmacological study.

Results: Plant explains about antibacterial, antioxidant, antifungal, anticatalytic, and antiviral activities. The work is an endeavor to explore and assemble the various pharmacological action and pharmacognostic aspects of the leaves A. carambola reported to date.

Conclusion: The current research has shown that natural sources have therapeutic properties without much toxicity. This potential of plants is due to the presence of secondary metabolites. The results prove that A. carambola leaf extract has antioxidant, antibacterial, and antifungal activity. In addition to this, the present investigation revealed that A. carambola leaf extract can act as a potential drug for treating breast cancer.

References

Vasconcelos CM, Araújo MS, Conde-Garcia EA. Electrophysiological effects of the aqueous extract of Averrhoa carambola L. Leaves on the guinea pig heart. Phyto Med 2006;13:501-8.

Wei SD, Chen H, Yan T, Lin YM, Zhou HC. Identification of antioxidant components and fatty acid profiles of the leaves and fruits from Averrhoa carambola. Food Sci Technol 2014;55:278-85.

Moresco HH, Queiroz GS, Pizzolatti MG, Brighente IM. Chemical constituents and evaluation of the toxic and antioxidant activities of Averrhoa carambola leaves. Braz J Pharmacogn 2012;22:319-24.

Ramadan NS, Wessjohann LA, Mocan A, Vodnar DC, El-Sayed NH, El- Toumy SA, et al. Nutrient and sensory metabolites profiling of Averrhoa carambola L. (starfruit) in the context of its origin and ripening stage by GC/MS and chemo metric analysis. Molecules 2020;25:2423.

Pal A, Chinnaiyan S, Mallik A, Bhattacharjee B. Anti ulcer activity of leaves of Averrhoa carambola Linn. Int J Pharmacol Res 2019;9:e5209.

Babu G, Jijitha TP. Identification, isolation and anticancer activity of bioactive constituents from fruit extract of Averrhoa carambola Linn. Int Res J Pharm 2016;7:84.

Ncube NS, Afolayan AJ, Okoh AI. Assessment techniques of antimicrobial properties of natural compounds of plant origin: Current methods and future trends. Afr J Biotechnol 2008;7:1797-806.

Published

01-02-2024

How to Cite

SRILEGA I, & KAVITHA M. (2024). EVALUATION OF THE POTENTIAL ROLE OF AQUEOUS LEAVES EXTRACT OF AVERRHOA CARAMBOLA FOR IN VITRO ANTICANCER STUDIES. Innovare Journal of Life Sciences, 12, 6–8. https://doi.org/10.22159/ijls.2024.v12i1.49713

Issue

Section

Original Article(s)