FATAL PROGNOSIS OF H1N1 INFLUENZA IN LATE TRIMESTER OF PREGNANCY: DESCRIPTIVE ANALYSIS OF FOUR CASES

Authors

  • Ajit Singh Department of Cardiology, Kasturba Medical College & Hospital, Manipal University, Manipal-576104, India
  • Kanav Khera
  • Jatin Agarwal
  • Shivanshu Awasthi
  • Jewel Maria Francis
  • Girish Thunga

Keywords:

Viral infections, Swine flu, Septic shock, Multiple organs dysfunction, Acute respiratory distress syndrome

Abstract

Influenza infection in late trimester associated with complications is attributable risk factors for critical illness among pregnant women. We have analyzed the medical records of four pregnant women retrospectively who were admitted in a medical intensive care unit of tertiary care center with influenza-like symptoms of breathlessness, fever, headache, myalgia and cough. Their mean age was 26.5 (19-30). They were confirmed to have H1N1infection by real-time reverse transcriptase polymerase chain reaction assay. Chest x-ray of all patients showed abnormalities like pulmonary edema and suggestive of acute respiratory distress syndrome. Arterial blood gas analysis of all four patients shown severe hypoxia and all of them was mechanically ventilated. Oseltemivir was started for all four from the day of admission. Pipracillin-tazobactum combination along with other antibiotics was given as prophylaxis and treatment of different infections. Midazolam and morphine were given together to reduce the restlessness and ventilator-associated distress. Furosemide was given to all for breathing problems and pulmonary edema. Despite of all the management provided none of the patients survived due to the progression of H1N1 into septic shock and multiple organs dysfunction syndromes. 

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Author Biography

Ajit Singh, Department of Cardiology, Kasturba Medical College & Hospital, Manipal University, Manipal-576104, India

Research Associate and PhD Scholar Department of Cardiology

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Published

01-08-2016

How to Cite

Singh, A., K. Khera, J. Agarwal, S. Awasthi, J. M. Francis, and G. Thunga. “FATAL PROGNOSIS OF H1N1 INFLUENZA IN LATE TRIMESTER OF PREGNANCY: DESCRIPTIVE ANALYSIS OF FOUR CASES”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 8, no. 8, Aug. 2016, pp. 399-01, https://mail.innovareacademics.in/journals/index.php/ijpps/article/view/12133.

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Section

Case Study(s)