IMPROVING ANTIBIOTIC PRESCRIBING PATTERN AND ASSESSMENT OF CO-MORBIDITIES ASSOCIATED WITH RESPIRATORY TRACT INFECTIONS
DOI:
https://doi.org/10.22159/ijpps.2017v9i2.15495Keywords:
Lower respiratory tract infection (LRTI), Antibiotics, Co-morbiditiesAbstract
Objective: The objective of this study was to describe the antibiotic prescribing pattern and co-morbidities associated with lower respiratory tract infections by means of cross-observational study.
Methods: A cross-sectional, open labelled and observational study was undertaken in a multi-speciality hospital for a period of 9 mo (November 2013-July2014). Lower respiratory tract infected patients who satisfied the selection criteria were included in the study. They were followed clinically and biochemically in the study.
Results: During the study period, most predominant antibiotics used were cephalosporin's which constitute about 63 % (with 3rd generation being the highest). Hypertension was found to be the most frequent co-morbidity (43%). Route of administration for most of the patients was parenteral followed by tablets and a very few on capsules. A few were changed from parenteral to oral when they met with the clinical criteria's for switching over therapy.
Conclusion: This study describes the antibiotic prescribing pattern and co-morbidities associated with lower respiratory tract infected patients.
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References
NICE clinical guideline 69–respiratory tract infections–antibiotic prescribing; 2008.
Christopher AE, Casimir N, Richard O. Microbiology of lower respiratory tract infections in Benin City, Nigeria. Malays J Med Sci 2011;18:27-31.
Anette H, Joergen N, Lene AB. Aetiology and prediction of pneumonia in lower respiratory tract infection in primary care. Br J Gen Pract 2007;57:547-57.
Macfarlane J, Holmes W, Gard P, Macfarlane R, Rose D, Weston V, et al. Prospective study of the incidence, aetiology and outcome of adult lower respiratory tract illness in the community. Thorax 2001;56:109-14.
Woodhead M, Blasi F, Ewig S, Huchon G, Leven M, Ortqvist A, et al. Guidelines for the management of adult lower respiratory tract infections. Eur Respir J 2005;6:1138-80.
Abhishek PS, Usha G, Saumya D. Monitor the use of antibiotics in intensive care units with a special focus on restricted antibiotics in tertiary care hospital of India. Asian J Pharm Clin Res 2016;9:256-9.
Warren JM, Teresa TO. Antibiotics for lower respiratory tract infections: still too frequently prescribed? Can Fam Physician 2004;50:569-75.
Dilip N. Sequential switch therapy for lower respiratory tract infections. Chest 1998;113:211-8.
Hanmant A, Priyadarshini KOP. Prescription analysis to evaluate the rational use of antimicrobials. Int J Pharm Biol Sci 2011;2:315-9.
Brieman RF, Butler JC, Tenover FC, Elliott JA, Facklam RR. The emergence of drug-resistant pneumococcal infections in the United States. JAMA 1994;271:1831-5.
Mazzaglia G, Arcoraci V, Greco S, Cucinotta G, Cazzola M, Caputi AP. Prescribing habits of general practitioners in choosing an empirical antibiotic regimen for lower respiratory tract infections in adult in sicily. Pharmacol Res 1999;40:47-52.
Ravi PS, Praveen P, Nagesh KS, Joshy ME, Kottallur NB. Prescribing patterns of antibiotics and sensitivity patterns of common microorganisms in the internal medicine ward of a teaching hospital in Western Nepal: a prospective study. Ann Clin Microbiol Antimicrob 2003;2:2-7.
Arcojit G, Asoke KD, Prasanta KG, Sampurna P. An observational study of drug use in upper respiratory tract infection in patients attending ent outpatient department in a tertiary care hospital in Kolkata. Asian J Pharm Clin Res 2015;8:37-40.
Tamizhazhagan V, Ashok K, Rrajesh S. Studies on bacterial population in intensive care unit of thanjavur medical college. Int J Curr Pharm Res 2014;6:55-7.
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