ANTIMICROBIAL AND ANTI-INFLAMMATORY STUDIES ON SARGASSUM WIGHTII EXTRACTS

Authors

  • Ramyapriyadharshini Raman Department of Biotechnology, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India
  • Sujitha Parthiban Department of Biotechnology, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India.
  • Karthikeyan S. Department of Biotechnology, Srimad Andavan Arts and Science College, Tiruchirapalli 620005, Tamil Nadu, India.
  • Meenakshi Sundaram Muthuraman Department of Biotechnology, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India.
  • Aravind Sivasubramanian Department of Chemistry, School of Chemical & Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur 613401, Tamil Nadu, India.

Keywords:

Antimicrobial, Anti-inflammatory, Sargassum wightii

Abstract

Objective: To evaluate the antimicrobial and anti-inflammatory effect of hexane, chloroform and ethanolic extract of Sargassum wightii.

Methods: Hexane, chlorofom and ethanolic extractions of these algae were done and evaluated for biological activity. Assay of antimicrobial activity was perfomed by disc diffusion method against various microorganisms. Assay of anti-inflammatory activity was performed in albino rats with paw edema, induced by Carrageenan.

Results: Chloroform and ethanol extracts exhibited antimicrobial activity against various microorganisms. All the extracts revealed anti-inflammatory activity, in which chloroform extract showed maximum activity in dose dependent manner.

Conclusions: Among the three different extracts tested, chloroform extract of S. wightii possess significant antimicrobial and anti-inflammatory activities. Further in-depth studies, could result in the development of a good antimicrobial and anti-inflammatory agent from this chloroform extract of S.wightii.

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Published

01-07-2014

How to Cite

Raman, R., S. Parthiban, K. S., M. S. Muthuraman, and A. Sivasubramanian. “ANTIMICROBIAL AND ANTI-INFLAMMATORY STUDIES ON SARGASSUM WIGHTII EXTRACTS”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, no. 7, July 2014, pp. 611-4, https://mail.innovareacademics.in/journals/index.php/ijpps/article/view/1998.

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