WOUND HEALING EFFECT OF KING ALFERD'S MUSHROOM (DALDINIA CONCENTRICA) USED BY TRIBES OF SIRUMALAI HILLS, TAMILNADU, INDIA
DOI:
https://doi.org/10.22159/ijpps.2017v9i7.20628Keywords:
Ethnomedicine, Paliyars, Phytochemicals, Wistar rats, Wound healingAbstract
Objective: The present investigation is an attempt to an ethnomycological mushroom survey carried out among the paliyar tribals of five settlements in Sirumalai hills. Daldinia concentrica, mushroom reported by the tribals for the wound healing activity was evaluated in vivo in rat model.
Methods: The indigenous information of the tribal people was collected through personal interviews during field trips and also the ethno reported mushroom Daldinia concetrica was analysed for its phytochemical constituents by Harborne method and its potential wound healing activity in Albino Wistar rats by excision wound model.
Results: The exploration revealed that 92% of the respondents consume mushroom as food and four mushrooms are used in ethnomedicine in the study area namely, Daldinia concentrica, Calvatia gigantean, Termitomyces microcarpus and Podaxis pistillaris. Daldinia concentrica for wound healing, is the first ethnomycological report, thus the further study on Daldinia revealed that the mushroom sample consists of alkaloid 0.97±0.07 mg/kg, flavanoid 2.97±0.12 mg/kg, phenol 0.32±0.01 mg/kg, tannin 0.17±0.02 mg/kg, terpenoid 0.07±0.01 mg/kg and saponin 0.09±0.02 mg/kg; and it's in vivo wound healing activity was found to be outstanding around 75–87% compared to that of the commercial ointment neosporin.
Conclusion: We believe that wound healing activity of Daldinia mushroom was due to the synergestic effect of phytochemicals present in them. Our results throw in the insight of the traditional use of mushrooms in various treatments.
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References
Jain SK. Dictionary of Indian folk medicine and Ethnobotany. Deep publication New Delhi; 1991.
Sanjay Paswan, Paramanshi Aideva. Encyclopedia of Dalit’s in India: Movements, Kalpaz Publications, India; 2002.
De Kesel A, Degreef J. Ethnomycological research and literature surveys from Africa. Mycoafrica 2007;2:4-5.
Wasser SP. Current findings, future trends and unsolved problems in studies of medicinal mushrooms. Appl Microbiol Biotechnol 2010;89:1323-32.
Champion HG, Seth SK. A revised survey of forest types of India, Government of India Press, Delhi; 1968.
Karuppusamy S, Rajasekaran KM, Karmegam N. Enumeration, ecology and ethnobotany of ferns of sirumalai hills, South India. J Econ Taxon Bot 2001;25:631-34.
Biswas TK, Mukherjee B. Plant medicines of Indian origin for wound healing activity: a review. Int J Lower Extremity Wounds 2003;2:25.
Taber CW. Taber’s cyclopedic medical dictionary. 10th edition. FA Davies Company, USA; 1965.
Ebi GC, Ofoefule SI. Investigation into the folkloric antimicrobial activities of Landolphia owerrience. J Phytol Res 1997;11:149-51.
Peterson JH. Welcome to Mycokey–the mycological information site; 2012. Available from: http://www.mycokey.com. [Last accessed on 20 Apr 2015]
Harborne JB. Phytochemical methods: a guide to modern techniques of plant analysis. Chapman and Hall Ltd, London; 1973.
Kiranmai M, Kazim SM, Ibrahim M. Combined wound healing activity of Gymnema sylvestere and Tagete serecta linn. Int. J Pharml Appl 2011;2:135-40.
Shrestha PM, Dhillion SS. Medicinal plant diversity of highlands of Dolakha district. Nepal J Ethnopharma 2003;86:81-96.
Arinathan V, Mohan VR. Ethno-medicinal survey among palliyar tribals of srivilliputhur grizzled giant squirrel wildlife sanctuary, Tamil Nadu. J Econ Taxon Bot 2003;2:707-10.
Somasekhar S, Saraswathi U, Laxminarayana U. Evaluation of antioxidant and wound healing effects of alcholic and aqueous extract of Ocimum sanctum Linn in Rats. eCAM 2008;5:95-101.
Chang R. Functional properties of edible mushrooms. Nutr Rev 1996;54:S91-S93.
Kavitha D, Balakumar R, Sivaprakasam E, Sridhar S, Suresh Kumar J. Antibacterial and antifungal potential of fruit body extracts from Daldinia concentrica (bolton) cesatiand de notaris. Int J Pharm Sci Res 2011;2: 2376-9.
Jonathan SG. Evaluation of the inhibitory potentials of eight higher nigerian fungi against pathogenic microorganisms. Afr J Biomed Res 2008;11:192–202.
Buwa LV, Staden JV. Antibacterial and antifungal activity of traditional medicinal plants used against venereal diseases in South Africa. J Ethnopharmacol 2006;103:139-42.
Parekh J. Efficacy of aqueous and methanol extracts of some medicinal plants for potential antibacterial activity. Turkish J Biol 2005;29:203-10.
Oryan A, Naeini AT, Nikahval B, Gorjian E. Effect of aqueous extract of Aloe vera on experimental cutaneous wound healing in rat. Vet Archive 2010;80:509-22.
Umachigi SP, Jayaveera KN, Ashok Kumar CK, Kumar GS, Vrushabendraswamy BM, Kishorekumar DV. Studies on wound healing properties of Quercus infectoria. Trop J Pharm Res 2008;7:913-9.
Somasekhar S, Saraswathi U, Laxminarayana U. Evaluation of antioxidant and wound healing effects of alcholic and aqueous extract of Ocimum sanctum Linn in Rats. eCAM 2008;5:95-101.
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