DETERMINATION OF TOTAL CARBOHYDRATES, FLAVONOIDS, ORGANIC ACIDS, MACRO-AND MICROELEMENTS IN WOLFBERRY (LYCIUM BARBARUM L.) FRUIT CULTIVATED IN ALBANIA

BLEONA TUPA; ELENA V. USPENSKAYA; OLGA G. POTANINA; NIKOLAY N. BOYKO; RAUDAS A. H. NASSER

doi:10.22159/ijpps.2022v14i6.44375

Authors

BLEONA TUPA Department of Pharmaceutical and Toxicological Chemistry, Peoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation https://orcid.org/0000-0003-0291-6285
ELENA V. USPENSKAYA Department of Pharmaceutical and Toxicological Chemistry, Peoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation https://orcid.org/0000-0003-2147-8348
OLGA G. POTANINA Moscow State University named after M.V. Lomonosov, Leninskie Gory, 1, Moscow, 119991, Russian Federation
NIKOLAY N. BOYKO Department of Pharmaceutical Chemistry and Pharmacognosy of the Center for Collective Use (Research and Education Center) “Center for Quality Control of Drugs”, Рeoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation
RAUDAS A. H. NASSER Department of Pharmaceutical Chemistry and Pharmacognosy of the Center for Collective Use (Research and Education Center) “Center for Quality Control of Drugs”, Рeoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation https://orcid.org/0000-0003-1198-4503

DOI:

https://doi.org/10.22159/ijpps.2022v14i6.44375

Keywords:

Lycium barbarum L., Extracts, Polysaccharides, Fructans, Flavonoids, Organic acids, Mineral elements

Abstract

Objective: The purpose of the study is to determine the biological activity components content of wolfberry (Lycium Barbarum L.) fruit originating from Albania. To unify the requirements for quality control of medicinal plant raw materials, it is advisable to study the qualitative composition and quantitative content of the components of this plant that determine the complexity of biological action-anti-inflammatory, neuroprotective, anti-cancer, vision-improving, and reproduction-enhancing effects.

Methods: Lycium barbarum L. fruits were analyzed for the content of total carbohydrates and fructans by spectrophotometry method. The organic acids, one flavonoid, and one scopoletin were identified and quantified by the HPLC method. Macro-and microelements were analyzed by ICP-OES.

Results: The results of the spectrophotometric analysis showed that total carbohydrate content and fructans content lie in the range of 21.763%-70.384% and 19.90-20.25%. Rutin, the main flavonoid compound in Lycium barbarum L. fruits, and scopoletin, a coumarin compound, contents lie respectively in the range of 2.10–5.48 mg/g and 0.48-0.76 mg/g. Potassium (K) is the predominant element in fruits, the content of which was 6740.75 μg/g.

Conclusion: Lycium barbarum L. fruit is a rich source of important biologically active substances. Further, the resulting data are going to be used to establish a monograph for Lycium barbarum L. fruits.

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