COMPARATIVE ASSESSMENT OF THE QUALITY OF PARKIA BIGLOBOSA TRUNK BARK POWDERS JACQ. BENTH (FABACEAE-MIMOSOIDEAE) INTENDED FOR THE PHARMACEUTICAL PRODUCTION OF PHYTO-DRUGS

SALFO OUEDRAOGO; TATA KADIATOU TRAORE; BOLADE CONSTANTIN ATCHADE; NOUFOU OUEDRAOGO; RASMANE SEMDE

doi:10.22159/ijpps.2022v14i10.44820

Authors

SALFO OUEDRAOGO Departement de Medecine et Pharmacopee Traditionnelles-Pharmacie (Mephatra-PH), Institut de Recherche en Science de la Sante (IRSS/CNRST), 03 BP 7047 Ouaga 03, Burkina Faso https://orcid.org/0000-0001-8643-4317
TATA KADIATOU TRAORE Laboratoire du Développement des Medicaments (LADME), Ecole Doctorale de la Sante, Université Joseph Ki-Zerbo, 03 BP 7021 Ouaga 03, Burkina Faso
BOLADE CONSTANTIN ATCHADE Laboratoire du Développement des Medicaments (LADME), Ecole Doctorale de la Sante, Université Joseph Ki-Zerbo, 03 BP 7021 Ouaga 03, Burkina Faso
NOUFOU OUEDRAOGO Departement de Medecine et Pharmacopee Traditionnelles-Pharmacie (Mephatra-PH), Institut de Recherche en Science de la Sante (IRSS/CNRST), 03 BP 7047 Ouaga 03, Burkina Faso
RASMANE SEMDE Laboratoire du Développement des Medicaments (LADME), Ecole Doctorale de la Sante, Université Joseph Ki-Zerbo, 03 BP 7021 Ouaga 03, Burkina Faso

DOI:

https://doi.org/10.22159/ijpps.2022v14i10.44820

Keywords:

Quality control, Parkia biglobosa, Trunk bark powders, Pharmaceutical production

Abstract

Objective: This study was conducted to determine the physicochemical characteristics and organic and inorganic contaminants of Parkia biglobosa trunk bark powders collected in four localities (Gonse, Yako, Bobo and Nobere) of Burkina Faso.

Methods: The parameters studied were the physicochemical characters, the contents of heavy metals, pesticides and the microbial quality according to the methods of the European Pharmacopoeia.

Results: The study of these parameters revealed a residual moisture content of less than 10% and a uniform pH, macroscopical character and particle sizes for all raw materials. Total ash ranged from 0.09 to 0.96 for powders from Yako and Bobo, respectively. Contaminant assessment revealed that Parkia biglobosa trunk bark contains high levels of manganese (Mn) and lead (Pb). The microbial analysis shows that the trunk bark powders from Gonse, Yako and Bobo complied with the specifications of the European Pharmacopoeia.

Conclusion: These quality control studies allowed the correct identification, characterization and determination of the appropriate harvesting sites for pharmaceutical production of phytomedicine.

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