A REVIEW OF POTENTIAL ANTICANCERS FROM ANTIMICROBIAL PEPTIDES

Authors

  • Khamsah Suryati Mohd Faculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin, Campus Tembila, 22200 Besut, Terengganu, Malaysia
  • Mohammed Al-kassim Hassan Universiti Sultan Zainal Abidin
  • Wan-atirah Azemin Universiti Sultan Zainal Abidin
  • Saravanan Dharmaraj Universiti Sultan Zainal Abidin

Keywords:

Antimicrobial peptides, Anticancerantitumour peptides, Host defense peptides

Abstract

Cancer is one of the leading causes of morbidity and mortality globally. The drawbacks of conventional chemotherapy such as resistance, lack of specificity, severe toxicity warrant the need to explore alternative approach for the treatment of cancer. Antimicrobial peptides are part of the innate defense mechanism of all organisms and have been developed as potential alternatives in combatting infectious diseases. In addition, anticancer effects of many peptides have been reported with remarkable prospects in some in vitro studies especially on breast, cervical and lung cancer cell lines, and in vivo murine tumour xenografts. This review summarizes the reports on the activities of some selected anticancer peptides on various cancer cell lines.

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Author Biography

Mohammed Al-kassim Hassan, Universiti Sultan Zainal Abidin

Masters student at Universiti Sultan Zainal Abidin

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Published

01-04-2015

How to Cite

Mohd, K. S., M. A.- kassim Hassan, W.- atirah Azemin, and S. Dharmaraj. “A REVIEW OF POTENTIAL ANTICANCERS FROM ANTIMICROBIAL PEPTIDES”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 7, no. 4, Apr. 2015, pp. 19-26, https://mail.innovareacademics.in/journals/index.php/ijpps/article/view/4921.

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Review Article(s)