PRESCRIBING PATTERN OF ANTIHYPERTENSIVE DRUGS BASED ON COMPELLING INDICATIONS WITH HYPERTENSION
Keywords:
Hypertension, Comorbidities, Prescribing patterns, Diabetes mellitusAbstract
Objective: The aim of the study is to assess the various prescribing patterns in hypertension with different compelling indications.
Methods: It is a prospective observational study and carried out for a period of 1 y from Feb-2014 to Feb-2015. All the required data was collected from patients through personal interview and prescriptions. The data collected from the participants was entered into Microsoft excel spreadsheet and descriptive statistics were used. The mean and standard deviation (SD) were calculated.
Results: A total of 394 hypertensive patients with different comorbidities were included in which 251(63.70%) males and 143(36.29%) females were present with a mean (SD) age of 59.21±1.54. The most commonly reported first three co-morbidities along with hypertension were diabetes mellitus 191 (48.47%), stroke accounts for 57 (14.46%) and coronary artery disease in 32 (8.12%). Monotherapy was given in almost 200 (50.76%) patients and dual drug therapy was indicated in 166 (42.13%) patients, triple therapy was used only in 24 (6.09%) patients in the total sample size. Quadruple therapy is the least preferred combination therapy accounts only in 4 (1.01%) patients.
Conclusion: We conclude that calcium channel blockers and angiotensin II receptor blockers were the most commonly prescribed class of drugs either alone or in combination with other class of drugs for effective control of blood pressure patients with different compelling indications. Monotherapy was preferred than combination therapy.
Â
Downloads
References
Essam Al-Drabah, YacoubIrshaid, Nada Yasein, Suheil Zmeili. Prescription pattern of antihypertensive drugs in family practice clinics at jordan university hospital. J Med Sci 2013;2:469-88.
Ethiraj Dhanaraj, Amit Raval, Rajbharan Yadav, Anil Bhansali, Pramil Tiwari. Prescription pattern of antihypertensive agents in T2DM patients visiting tertiary care centre in North India. Int J Hypertens 2012;1-9. doi.org/10.1155/2012/520915. [Article in Press]
Ranjeeta Kumari, Idris MZ, Vidya Bhushan, Anish Khanna, Monika Agrawal, Shivendra Kumar Singh. Assessment of prescription pattern at the public health facilities of lucknow district. Indian J Pharmacol 2008;40:243-7.
Yuen YH, Chang S, Chong CK, Lee SC, Critchley JA, Chan JC. Drug utilization in a hospital general medical outpatient clinic with particular reference to antihypertensive and antidiabetic drugs. Journal Clin Pharmacother1998;23:287-94.
Bajaj jk, Sood M, Singh SJ, Jerath P. Prescription patterns of antihypertensive drugs and adherence to JNC 7 guidelines in a tertiary care hospital in north India. Int J Med Clin Res 2012;3:118-20.
Preethi M, Praveen Kumar NVRT, Lekshmi S, Manna PK, Mohanta GP, Parimalakrishnan S, et al. A study on the prescription pattern of antihypertensives. Indian J Pharm Practice 2010;4:41-4.
Mohammad Arief, Harika B, Bonthusatyanarayana, Shaikwajid pasha, Deepthipoloju, Swapnapokkula, et al. Evaluation of prescribing pattern of antihypertensive drugs in a tertiary care hospital. Acta Chim Pharm Indica 2013;3:172-81.
Sharminder Kaur, Seema Gupta, Dinesh Kumar, Mohan Lal, Zahid Gilani. Prescribing pattern of antihypertensive drugs in a tertiary care hospital in jammu-A descriptive study. Int J Curr Med Sci Practice 2012;17:38-41.
Anand Kale1, Yasmeen A Maniyar. Prescribing patterns of antihypertensive drugs in a tertiary care hospital. Scholars Academic J Pharm 2013;2:416-8.