IN VITRO DPPH RADICAL SCAVENGING AND ANTI-BACTERIAL ACTIVITY OF OMAN'S CYMBOPOGON
Abstract
Objective: The objective of this work is to evaluate antioxidant and anti-microbial activity of methanolic extract of Omani Cymbopogan schoenanthus.
Methods: Antibacterial activity of mehanolic extract of Cymbopogan was evaluated by agar well diffusion method along with positive controls (Streptomycin, tetracycline and chloramphenicol). Antioxidant activity of the mehanolic extract of C. schoenanthus was done by 1, 1-diphenyl-2picrylhydrazyl (DPPH) free radical scavenging assay.
Results: The results indicate that the methanolic extract of C. schoenanthus is able to restrict the growth of organisms such E. coli, Klebsiella, Staphylococcus and Bacillus partially and it is not an effective antibacterial agent. In addition, the extract can scavenge the DPPH in vitro better than ascorbic acid (1 mg/ml).
Conclusion: To the best of our knowledge this is the first report on Omani C. schoenanthus as an antibacterial and antioxidant agent. Characterization of active principle responsible for observed biological activities is ongoing in our laboratory.
Keywords: Antibacterial, Antioxidant, Cymbopogon, Oman.
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