PHYTOPHARMACOLOGICAL PROPERTIES OF MELOTHRIA MADERASPATANA: A REVIEW

Authors

  • Indhumathi Paramasivam Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur - 613 401,Tamil Nadu, India
  • Simran Sinsinwar Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur - 613 401,Tamil Nadu, India
  • Meenakshi Sundaram Muthuraman Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thirumalaisamudram, Thanjavur - 613 401,Tamil Nadu, India

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i8.18964

Keywords:

Medicinal plants, Melothria maderaspatana, Biological activities, Diseases

Abstract

A medicinal plant plays a vital role in traditional systems. It is necessary to study the pharmacology activity of individual plants for treating diseases. Melothria maderaspatana Linn belongs to the family of cucurbitaceae, mostly present in South India and it shows biological activities such as antibacterial, antioxidant, larvicidal, antiulcerogenic, antidiabetic, hypolipidemic, antihypertensive, immunomodulatory and antihepatotoxic for treating various diseases which are discussed in this review paper. 

Downloads

Download data is not yet available.

References

Sinha BN, Thanigavelan J, Basu SP, Sukumar E. Studies on Melothria maderaspatana (Linn). Cogn. Anc Sci Life 1996;15:238-40.

Iman RA, Priya BL, Chithra R, Shalini K, Sharon V, Chamundeeswari D, et al. In vitro antiplatelet activity guided fractionation of aerial parts of Melothria maderaspatana. Indian J Pharm Sci 2006;68(5):668-70.

Sinha BN, Sasmal D, Basu SP. Pharmacological studies on Melothria maderaspatana. Fitoterapia 1997;68(1):75-8.

Sankaranarayanan S, Bama P, Rmamchandran J, Kalaichelvan PT, Deccaraman M, Vijayalakshmi M, et al. Ethnobotanical study of medicinal plants used by traditional users in Villupuram district of Tamil Nadu, India. J Med Plants Res 2010;4(12):1089-101.

Harshiny M, Matheswaran M, Arthanareeswaran G, Kumaran S, Rajasree S. Enhancement of antibacterial properties of silver nanoparticles-ceftriaxone conjugate through Mukia maderaspatana leaf extract mediated synthesis. Ecotoxicol Environ Saf 2015;121:135-41.

Riyazullah MS, Sivakumar V, Raja PP. Comparative antimicrobial activity of aerial parts of Melothria maderaspatana of Indian and Srilankan Origin. Int J Pharmatech Res 2010;2(4):2343-6.

Hemamalini K, Varma MV. Antimicrobial activity of methanolic leaves extract of Melothria maderaspatana Linn. Pharmacologyonline 2007;3:323-6.

Veeramani C, Aristatile B, Pushpavalli G, Pugalendi KV. Effects of Melothria maderaspatana leaf extract on antioxidant status in sham-operated and uninephrectomized DOCA-salt hypertensive rats. Saudi J Biol Sci 2011;18(1):99-105.

Raja B, Pugalendi KV. Evaluation of antioxidant activity of Melothria maderaspatana in vitro. Cent Eur J Biol 2010;5(2):224-30.

Prakash NK, Bhuvaneswari S, Sripriya N, Prameela L, Bhagya R, Radhika B, et al. Antioxidant activity of common plants of Northern Tamil Nadu, India. Int J Pharm Pharm Sci 2014;6(4):128-32.

Balaraman AK, Singh J, Dash S, Naskar A, Maity TK. Evaluation of antioxidant activity of different fractions of Melothria maderaspatana. Asian J Chem 2011;23(5):2207-11.

Sowndhararajan K, Joseph JM, Rajendrakumaran D, Manian S. In vitro antioxidant characteristics of different parts of Melothria maderaspatana (L.) Cogn. Int J Pharm Pharm Sci 2010;2:117-23.

Choudhary S, Tanwer BS, Singh T, Vijayavergia R. Total phenolic, total flavonoid content and the DPPH free radical scavenging activity of Melothria maderaspatana (Linn.) Cogn. Int J Pharm Pharm Sci 2013;5(1):296-8.

Chitra G, Balasubramani G, Ramkumar R, Sowmiya R, Perumal P. Mukia maderaspatana (Cucurbitaceae) extract-mediated synthesis of silver nanoparticles to control Culex quinquefasciatus and Aedes aegypti (Diptera: Culicidae). Parasitol Res 2015;114(4):1407-15.

Gomathy G, Venkatesan D, Palani S. Gastroprotective potentials of the ethanolic extract of Mukia maderaspatana against indomethacin-induced gastric ulcer in rats. Nat Prod Res 2015;29:2107-11.

Srilatha BR, Ananda S. Antidiabetic effects of Mukia maderaspatana and its phenolics: An in vitro study on gluconeogenesis and glucose uptake in rat tissues. Pharm Biol 2014;52:597-602.

Balaraman AK, Singh J, Dash S, Maity TK. Antihyperglycemic and hypolipidemic effects of Melothria maderaspatana and Coccinia indica in streptozotocin induced diabetes in rats. Saudi Pharm J 2010;18:173-8.

Petrus AJ. Mukia maderaspatana (Linn.) M. Roemer. A potentially antidiabetic and vasoprotective functional leafy-vegetable. Pharmacogn J 2012;4(34):1-12.

Veeramani C, Al-Numair KS, Chandramohan G, Alsaif MA, Pugalendi KV. Antihyperlipidemic effect of Melothria maderaspatana leaf extracts on DOCA-salt induced hypertensive rats. Asian Pac J Trop Med 2012;5(6):434-9.

Pandey D, Pandey S, Hemalatha S. Hypolipidemic activity of aqueous extract of Melothria maderaspatana. Pharmacol Online 2010;3:76-83.

Veeramani C, Al-Numair KS, Chandramohan G, Alsaif MA, Alhamdan AA, Pugalendi KV. Antihypertensive effect of Melothria maderaspatana leaf fractions on DOCA-salt-induced hypertensive rats and identification of compounds by GC-MS analysis. J Nat Med 2012;66(2):302-10. 22. Veeramani C, Aristatle B, Pushpavalli G, Pugalendi KV. Antihypertensive efficacy of Melothria maderaspatana leaf extract on sham-operated and uninephrectomized DOCA-salt hypertensive rats. J Basic Clin Physiol Pharmacol 2010;21(1):27-41.

Thabrew MI, de Silva KT, Labadie RP, de Bie PA, van der Berg B. Immunomodulatory activity of three Sri-Lankan medicinal plants used in hepatic disorders. J Ethnopharmacol 1991;33(1-2):63-6.

Jayatilaka KA, Thabrew MI, Pathirana C, De Silva DG, Perera DJ. An evaluation of the potency of Osbeckia octandra and Melothria maderaspantana as antihepatotoxic agents. Planta Med 1989;55(2):137-9.

Veeramani C, AI-Numair KS, Chandramohan G, Alsaif MA, Pugalendi KV. Renal protective effect of Melothria maderaspatana leaf fraction on uninephrectomized deoxycorticosterone acetate-salt hypertensive rats. Prog Nutr 2014;16(3):204-11.

Thabrew MI, Gove CD, Hughes RD, McFarlane IG, Williams R. Protection against galactosamine and tert-butyl hydroperoxide induced hepatocyte damage by Melothria maderaspatana extract. Phytother Res 1995;9(7):513-7.

Jayatilaka KA, Thabrew MI, Perera DJ. Effect of Melothria maderaspatana on carbon tetrachloride-induced changes in rat hepatic microsomal drug-metabolizing enzyme activity. J Ethnopharmacol 1990;30(1):97-105.

Veeramani C, AI-Numair KS, Chandramohan G, Alsaif MA, Pugalendi KV. Effect of ethyl acetate fraction of Melothria maderaspatana leaf on membrane bound ATPases in DOCA-salt induced hypertensive rats. Prog Nutr 2015;17(4):331-8.

Raja B, Kaviarasan K, Arjunan MM, Pugalendi KV. Effect of Melothria maderaspatana leaf-tea consumption on blood pressure, lipid profile, anthropometry, fibrinogen, bilirubin, and albumin levels in patients with hypertension. J Altern Complement Med 2007;13(3):349-54.

Srinivasan S, Indumathi D, Sujatha M, Sujithra K, Muruganathan U. Novel synthesis, characterization and antibacterial activity of silver nanoparticles using leaf extract of Melothria maderaspatana (Linn.) cong. Int J Pharm Pharm Sci 2016;8(6):104-9.

Srinithya B, Muthuraman MS. An overview on the biological perspectives of Sida cordifolia Linn. Ar. Int J Pharm Pharm Sci 2014;6(11):15-7.

Godipurge SS, Biradar NJ, Biradar JS, Mahurkar N. Chemical composition and hepatoprotective effects of polyphenolic fraction from Rivea hypocrateriformis in paracetamol induced liver damage in wistar albino rats. Int J Pharm Pharm Sci 2016;8(10):228-34.

Published

01-08-2017

How to Cite

Paramasivam, I., S. Sinsinwar, and M. S. Muthuraman. “PHYTOPHARMACOLOGICAL PROPERTIES OF MELOTHRIA MADERASPATANA: A REVIEW”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 8, Aug. 2017, pp. 34-36, doi:10.22159/ajpcr.2017.v10i8.18964.

Issue

Section

Review Article(s)