SILVER NANOPARTICLES FROM MEDICINALLY IMPORTANT EUPHORBIA CYATHOPHORA EXTRACT: BIOSYNTHESIS, CHARACTERIZATION, AND ANTICANCER ACTIVITY.

Robert Lotha; Aravind Sivasubramanian; Meenakshi Sundaram Muthuraman

doi:10.22159/ajpcr.2018.v11i2.22216

Authors

Robert Lotha Department of Chemistry, School of Chemical and Biotechnology, SASTRA University,Thanjavur, Tamil Nadu, India.
Aravind Sivasubramanian Department of Chemistry, School of Chemical and Biotechnology, SASTRA University,Thanjavur, Tamil Nadu, India.
Meenakshi Sundaram Muthuraman Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thanjavur, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i2.22216

Keywords:

Green synthesis, Nanoparticles, Euphorbia cyathophora, Scanning electron microscopy, Antioxidant, Anticancer

Abstract

Objective: The present study was aimed at the biosynthesis of silver nanoparticles (AgNPs) using aqueous extract of Euphorbia cyathophora leaves

and testing their anticancer potential using HT-29 cell line model.

Methods: Green synthesis of silver nanoparticles was obtained with the aqueous extract of E. cyathophora. The synthesized nanoparticles were

confirmed initially by ultraviolet-visible spectroscopy. Further, scanning electron microscopy, transmission electron microscopy, and X-Ray diffraction

studies also ensured the presence of silver nanoparticles. Zeta potential studies revealed the stability of the silver nanoparticles.

Results: Antioxidant and anticancer studies of the nanoparticles against HT-29 cell line exhibited remarkable results.

Conclusion: This ensures that the synthesized nanoparticles play an important role in medicinal biology.

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