SYNTHESIS OF COPPER NANOPARTICLES USING ASCORBIC ACID AND CETYL TRIMETHYL AMMONIUM BROMIDE

Authors

  • Saurabh Singh Department of Pharmacy, School of Ayurvedic Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.
  • Bimlesh Kumar Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.
  • Narendra Kumar Pandey Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.
  • Barinder Kaur Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.
  • Arun Kumar Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.
  • Dileep Singh Baghel Department of Pharmacy, School of Ayurvedic Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.
  • Malti G. Chauhan Member Ayurvedic Pharmacopoeia Committee, Pharmacopoeia Commission for Indian Medicine and Homoeopathy Ghaziabad Government of India, Uttar Pradesh, India.
  • Sachin Kumar Singh Department of Pharmacy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara – 144 411, Punjab, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11s2.28531

Keywords:

Copper nanoparticles, Cetyl trimethyl ammonium bromide, Ascorbic acid, Spray drying, Particle Size, Zeta potential

Abstract

Objective: The present study highlights the development of a method to synthesize copper nanoparticles (CuNPs).

Methods: CuNPs were developed using 0.01 M copper penta sulfate and 0.11 M of ascorbic acid (AA) and 0.03 M of cetyl trimethyl ammonium bromide solution. The synthesized CuNPs were differentiated through filtration and washed by water (deionized). CuNPs were kept in dialysis bag 70 KD in a 250 mL glass beaker along with distilled water. The assembly was kept on a magnetic stirrer for 24 h at 500 rpm. Then, the dialysis bag containing CuNPs solution was filtered by a filter assembly with 0.2 μm nylon filter. The filtered CuNPs were spray dried with the help of spray drier.

Results: The prepared CuNPs were found to be 440 nm with zeta potential of −10 mV and polydispersity index 0.314.

Conclusion: The investigation deciphers the promising and material technique to synthesis of CuNPs by methods for synthetic reduction utilizing strategy using AA (0.2 M) and sodium hydroxide (1 M), and Syloid 244FP.

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References

Feldheim DL, Foss JR. Metal Nanoparticles; Synthesis, Characterization, and Applications. New York, USA: Marcel Dekker Incorporated; 2002.

Siegel RW, Hu E, Roco MC. Nanostructure science and technology: R and D status and trends in nanoparticles, nanostructured materials, and nanodevices. 1st ed. Dordrecht, Netherland: Springer, Academic Press; 1999.

Vutpala S, Abbaraju KS. Preparation and characterization of ibuprofen loaded polymeric nanoparticles by solvent evaporation technique. Int J Pharm Sci 2014;6:416-21.

Yeh MS, Yang YS, Lee YP. Formation and characteristics of cu colloids from Cuo powder by laser irradiation in 2-propanol. J Phys Chem 1999;103:6851-7.

Liu Z, Bando Y. A novel method for preparing copper nanorods and nanowires. Adv Mater 2003;15:303-5.

Available from: https://www.doi.org/10.1063/1.115011. [Last accessed on 2017 May 03].

Oleszaka D, Paul HS. Nanocrystalline metals prepared by low energy ball milling. J Appl Phys 1996;79:2976-9.

Wang Y, Chen P, Liu M. Synthesis of well-defined copper nanocubes by a one-pot solution process. Nanotechnology 2006;17:6000-6.

Pileni MP. Reverse micelles as micro reactors. J Phys Chem 1993; 97:6961-73.

Kumar RV, Mastai Y, Gedankan A. Sonochemical synthesis of amorphous Cu and nanocrystalline Cu2O embedded in a polyaniline matrix. Chem Mater 2000;12:3892-5.

Molares ME, Buschmann V, Dobrev D. Single-crystalline copper nanowires produced by electrochemical deposition in polymeric ion track membranes. Adv Mater 2001;13:62-5.

Available from: https://www.ars.usda.gov/research/publications/ publication/?seqNo115=132674. [Last accessed on 2017 Jul 06].

Chu LY, Zhuo Y, Dong L. Controlled synthesis of various hollow Cu nano/microstructures via a novel reduction route. Adv Funct Mater 2007;17:933-8.

Bali R, Razak, N, Lumb A. Synthesis of metal nanoparticles inside live plants. In: International Conference on Nanoscience and Nanotechnology; 2006. p. 224-7.

Available from: https://www.worldscientific.com/doi/abs/10.1142/ S1793292012300058. [Last accessed on 2017 Sep 20].

Saranyaadevi K, Subha V, Ravindran RS, Renganathan S. Green synthesis and characterization of silver nanoparticle using leaf extract of Capparis zeylanica. Asian J Clin Res 2014;7:44-8.

Fatma S, Kalainila P, Ravindran E. Renganathan green synthesis of copper nanoparticle from Passiflora foetida leaf extract and its antibacterial activity. Asian J Phys Clin Res 2017;10:80-3.

Kumar B, Garg V, Singh S, Pandey NK, Bhatia A, Prakash T, et al. Impact of spray drying over conventional surface adsorption technique for improvement in micromeritics and biopharmaceutical characteristics of self-nanoemulsifying powder loaded with two lipophilic as well as gastrointestinal labile drug. Powder Technol 2018;326:424-2.

Published

27-07-2018

How to Cite

Singh, S., B. Kumar, N. K. Pandey, B. Kaur, A. Kumar, D. S. Baghel, M. G. Chauhan, and S. K. Singh. “SYNTHESIS OF COPPER NANOPARTICLES USING ASCORBIC ACID AND CETYL TRIMETHYL AMMONIUM BROMIDE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 14, July 2018, pp. 62-64, doi:10.22159/ajpcr.2018.v11s2.28531.

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Original Article(s)