PHYTOCHEMICAL AND ANTIMICROBIAL STUDIES ON GARCINIA LATTISSIMA MIQ. FRUIT EXTRACT

Neneng Sitisilfi Ambarwati; Berna Elya; Amarila Malik; Muhammad Hanafi

doi:10.22159/ajpcr.2017.v10i7.18528

Authors

Neneng Sitisilfi Ambarwati Department of , Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.
Berna Elya Department of, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.
Amarila Malik Department of, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.
Muhammad Hanafi Centre for Chemistry, Indonesian Institute of Sciences, Serpong, Banten, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i7.18528

Keywords:

Garcinia lattissima Miq, Antimicrobial, Phytochemical, Tannins, Saponins, Flavonoids, Alkaloids

Abstract

Objective: The present investigation was aimed to explore the phytoconstituents present in the fruit part of Garcinia lattissima Miq. and their antimicrobial efficacy.

Methods: The preliminary phytochemical constituents were qualitatively analyzed using the standard procedures described in Materia Medica Indonesia. Antimicrobial screening was performed using disc diffusion and dilution methods.

Results: Phytochemical screening of different extracts of G. lattissima Miq. fruits revealed the presence of tannins, saponins, flavonoids, and alkaloids, and the results are shown in Table 1. The ethyl acetate and methanolic extracts of G. lattissima Miq. fruits showed antimicrobial activity, and the n-hexane extract failed to prove the inhibition against the selected pathogens.

Conclusion: The results of the phytochemical and bio-efficacy study revealed most valuable information and also support the continued sustainable use of G. lattissima Miq. fruits in the traditional system of medicine.

Downloads

Download data is not yet available.

Author Biography

Neneng Sitisilfi Ambarwati, Department of , Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.

Department Health and Beauty Jakarta State University

References

Johnson M, Kalaiarasi V, Sivaraman A, Janakiraman N, Babu A, Narayani M. Phytochemical and antibacterial studies on Aristolochia tagala Cham. World J Pharm Res 2014;3(2):2172-8.

Stevens PF. The families and genera of fascular plants. In: Flowering Plants. Vol. 9. Berlin, Heidelberg: Springer-Verlag; 2007. p. 48-66.

Ramage CM, Sando L, Peace CP, Carroll BJ, Drew RA. Genetic diversity revealed in the apomictic fruit species Garcinia mangostana L. (Mangosteen). Euphytica 2004;136(1):1-10.

Eisai P. Medicinal Herb Index in Indonesia. 2nd ed. Indonesia: P.T. Eisai; 1995. p. 71.

Conn B, Damas K. PNGTreesKey-Garcinia latissima Miq. In: Annales Musei Botanici Lugduno-Batavi. Vol. 1. New South Wales, Papua New Guinea: National Herbarium; 1863.

Sari R, Ruspandi, Ariati SR. An Alphabetical List of Plant Species Cultivated in the Bogor Botanic Gardens. Bogor: LIPI; 2010.

Ito C, Miyamoto Y, Nakayama M, Kawai Y, Rao KS, Furukawa H. A novel depsidone and some new xanthones from Garcinia species. Chem Pharm Bull 1997;45(9):1403.

Rao KS. Antibacterial activity of some medicinal plants of Papua New Guinea. Int J Pharmacogn 1996;34(3):223-5.

Yin NG, Abdullah S, Phin CK. Phytochemical constituents from leaves of Elaeis guineensis and their antioxidant and antimicrobial activities. Int J Pharm Pharm Sci 2013;5(4):137-40.

Fransworth NR. Biological and phytochemical screening of plants. J Pharm Sci 1995;22(3):226-76.

Depkes RI. Materia Medika Indonesia. Vol. VI. Jakarta: Departemen Kesehatan Republik Indonesia; 1995.

Bamas SS, Kingsley SJ, Sankaranarayanan S. Antibacterial activity of different phytochemical extracts from the leaves of T. Procumbens. Linn.: Identification and Mode of action of the terpenoid compound as antibacterial. Int J Pharm Pharm Sci 2012;4:557-64.

Mathew S. An evaluation of the antimicrobial activity of various concentrations of Ocimum sanctum against various species of bacteria: An in vitro study. Int J Adv Appl Sci 2014;3(1):33-6.

Jeong MR, Kim HY, Cha JD. Antimicrobial activity of methanol extract from Ficus carica Leaves against oral bacteria. J Bacteriol Virol 2009;39(2):97-102.

Sanches NR, Cortez DA, Schiavini MS, Nakamura CV, Dias-Filho BP. An evaluation of antibacterial activities of Psidium guajava (L.). Braz Arch Biol Technol 2005;48(3):429-36.